DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2120 and ZNF415

DIOPT Version :9

Sequence 1:NP_572446.2 Gene:CG2120 / 31737 FlyBaseID:FBgn0030005 Length:315 Species:Drosophila melanogaster
Sequence 2:XP_024307363.1 Gene:ZNF415 / 55786 HGNCID:20636 Length:678 Species:Homo sapiens


Alignment Length:258 Identity:85/258 - (32%)
Similarity:123/258 - (47%) Gaps:33/258 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly    66 ALQQRNTTEHKPTDMCKP-------KRTPTTKRHRTTG-KDHTCDICDRRFSEAYNLRIHKMTHT 122
            ||.|:.....||. .||.       :.|.|..:...:| |.:.|:.|.:.||:..:|..|:..||
Human   439 ALHQKTHIGEKPY-TCKECGKAFSVRSTLTNHQVIHSGKKPYKCNECGKVFSQTSSLATHQRIHT 502

  Fly   123 DEKPHVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPCLA 187
            .|||:.|.||||.|.|.:.|..|...||.|:|:||:.|||.|.|.::|..|||:|||||||.|  
Human   503 GEKPYKCNECGKVFSQTSSLARHWRIHTGEKPYKCNECGKVFSYNSHLASHRRVHTGEKPYKC-- 565

  Fly   188 TDCHLSFHSIHARRIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHL 252
            .:|..:| |:|:.....::.|..      |.|             :.|..|.:..:....|:.|.
Human   566 NECGKAF-SVHSNLTTHQVIHTG------EKP-------------YKCNQCGKGFSVHSSLTTHQ 610

  Fly   253 KRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHLKVHER 315
            ..|..::.:.|  .||||.|.....|..|||.||.::|:.|..|...|..:.|..:|..:|.:
Human   611 VIHTGEKPYKC--NECGKSFSVRPNLTRHQIIHTGKKPYKCSDCGKSFSVRPNLFRHQIIHTK 671

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2120NP_572446.2 C2H2 Zn finger 101..121 CDD:275368 6/19 (32%)
zf-H2C2_2 113..138 CDD:290200 13/24 (54%)
C2H2 Zn finger 129..149 CDD:275368 9/19 (47%)
zf-H2C2_2 142..166 CDD:290200 12/23 (52%)
COG5048 151..>264 CDD:227381 33/112 (29%)
C2H2 Zn finger 157..177 CDD:275368 10/19 (53%)
C2H2 Zn finger 185..206 CDD:275368 5/20 (25%)
C2H2 Zn finger 235..255 CDD:275368 4/19 (21%)
C2H2 Zn finger 263..285 CDD:275368 10/21 (48%)
C2H2 Zn finger 293..313 CDD:275368 5/19 (26%)
ZNF415XP_024307363.1 KRAB 51..91 CDD:307490
COG5048 <235..497 CDD:227381 16/58 (28%)
C2H2 Zn finger 343..361 CDD:275368
COG5048 367..>662 CDD:227381 82/247 (33%)
C2H2 Zn finger 369..389 CDD:275368
C2H2 Zn finger 397..417 CDD:275368
C2H2 Zn finger 425..445 CDD:275368 3/5 (60%)
C2H2 Zn finger 453..473 CDD:275368 4/19 (21%)
C2H2 Zn finger 481..501 CDD:275368 6/19 (32%)
C2H2 Zn finger 509..529 CDD:275368 9/19 (47%)
C2H2 Zn finger 537..557 CDD:275368 10/19 (53%)
C2H2 Zn finger 565..585 CDD:275368 5/22 (23%)
C2H2 Zn finger 593..613 CDD:275368 4/19 (21%)
C2H2 Zn finger 621..641 CDD:275368 10/21 (48%)
C2H2 Zn finger 649..669 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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