Protein Alignment CG2120 and ZNF879

DIOPT Version :9

• Sequence 1: NP_572446.2
• Gene: CG2120 / 31737
• FlyBaseID: FBgn0030005
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001129588.1
• Gene: ZNF879 / 345462
• HGNCID: 37273
• Length: 563
• Species: Homo sapiens
• Alignment Length: 327
• Identity: 92/327 - (28%)
• Similarity: 141/327 - (43%)
• Gaps: 65/327 - (19%)

  Fly    26 CLEDLQLFAQLEDL-------SGERLPMEMELLNPGSEYDLLELVNGALQQRNTTEHKPTDMCKP 83
            |.|..:.|:|...|       :||:..:..|.   |..:.....:.|  .||..|..:|. .||.
Human   234 CKECRKAFSQSSSLTQHLRVHTGEKPYICSEC---GKAFSFTTSLIG--HQRMHTGERPY-KCKE 292

  Fly    84 -----KRTPTTKRHR---TTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLN 140
                 |.:.:...|:   |..|.:.|:.|.|.||:..:|..|...||.|||:.|.:|||.|..::
Human   293 CGKTFKGSSSLNNHQRIHTGEKPYKCNECGRAFSQCSSLIQHHRIHTGEKPYECTQCGKAFTSIS 357

  Fly   141 KLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDCHLSFHS----IHARR 201
            :|..|...||.|:|..|:.|||.|.|.:.|.:|:|:|||||||.|  .:|..:|..    |..:|
Human   358 RLSRHHRIHTGEKPFHCNECGKVFSYHSALIIHQRIHTGEKPYAC--KECGKAFSQSSALIQHQR 420

  Fly   202 IHT--------------------KLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQC 246
            |||                    .:.|...|...|                :.|..|.:..:...
Human   421 IHTGEKPYKCNECGKAFSWISRLNIHHRIHTGEKP----------------YNCKECGKAFSSHS 469

  Fly   247 YLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHLK 311
            .::.|.|.|..::.:.|  .:|.|.|..:|.|..||..||.::|:.|.:|...|.:.|:...|::
Human   470 GVNTHRKIHTGEKPYKC--NDCEKAFNQSSALIQHQRIHTGEKPYNCKVCGKAFRQSSSLMTHMR 532

  Fly   312 VH 313
            :|
Human   533 IH 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	7/19 (37%)
		zf-H2C2_2	113..138	CDD:290200	12/24 (50%)
		C2H2 Zn finger	129..149	CDD:275368	7/19 (37%)
		zf-H2C2_2	142..166	CDD:290200	11/23 (48%)
		COG5048	151..>264	CDD:227381	34/136 (25%)
		C2H2 Zn finger	157..177	CDD:275368	9/19 (47%)
		C2H2 Zn finger	185..206	CDD:275368	8/44 (18%)
		C2H2 Zn finger	235..255	CDD:275368	4/19 (21%)
		C2H2 Zn finger	263..285	CDD:275368	8/21 (38%)
		C2H2 Zn finger	293..313	CDD:275368	5/19 (26%)
ZNF879	NP_001129588.1	KRAB	14..74	CDD:214630
		COG5048	202..558	CDD:227381	92/327 (28%)
		C2H2 Zn finger	206..226	CDD:275368
		C2H2 Zn finger	234..254	CDD:275368	5/19 (26%)
		C2H2 Zn finger	262..282	CDD:275368	5/24 (21%)
		C2H2 Zn finger	290..310	CDD:275368	4/19 (21%)
		C2H2 Zn finger	318..338	CDD:275368	7/19 (37%)
		C2H2 Zn finger	346..366	CDD:275368	7/19 (37%)
		C2H2 Zn finger	374..394	CDD:275368	9/19 (47%)
		C2H2 Zn finger	402..422	CDD:275368	5/21 (24%)
		C2H2 Zn finger	430..450	CDD:275368	1/19 (5%)
		C2H2 Zn finger	458..478	CDD:275368	4/19 (21%)
		C2H2 Zn finger	486..506	CDD:275368	8/21 (38%)
		C2H2 Zn finger	514..534	CDD:275368	5/19 (26%)
		C2H2 Zn finger	542..562	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000