Protein Alignment CG2120 and ZNF841

DIOPT Version :9

• Sequence 1: NP_572446.2
• Gene: CG2120 / 31737
• FlyBaseID: FBgn0030005
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001356754.1
• Gene: ZNF841 / 284371
• HGNCID: 27611
• Length: 925
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 89/263 - (33%)
• Similarity: 128/263 - (48%)
• Gaps: 32/263 - (12%)

  Fly    57 YDLLELVNGALQQRNTTEHKPTDMCK----PKRTPTTKRHRTTGKDHTCDICDRRFSEAYNLRIH 117
            |...:||...:.....|.:|..:..|    ..|....:|..|..|.:.|:.|.:.||:..:|.:|
Human   440 YQNSQLVRHQIIHTGETPYKCNECGKVFFQRSRLAGHRRIHTGEKPYKCNECGKVFSQHSHLAVH 504

  Fly   118 KMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKP 182
            :..||.|||:.|.||||.|...:.|.:|...||.|:|:||::|||.|.|..||:||.|.||||||
Human   505 QRVHTGEKPYKCNECGKAFNWGSLLTVHQRIHTGEKPYKCNVCGKVFNYGGYLSVHMRCHTGEKP 569

  Fly   183 YPCLATDCHLSFHSIHAR--RIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQ 245
            ..|.......:::|..||  |:||           .|.|             :.|.||.:|..|.
Human   570 LHCNKCGMVFTYYSCLARHQRMHT-----------GEKP-------------YKCNVCGKVFIDS 610

  Fly   246 CYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHL 310
            ..||||.:.|..::.|.|  .||||.|...|.|..|:..||.::|:.|..|...:.::|:..:||
Human   611 GNLSIHRRSHTGEKPFQC--NECGKVFSYYSCLARHRKIHTGEKPYKCNDCGKAYTQRSSLTKHL 673

  Fly   311 KVH 313
            .:|
Human   674 VIH 676

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	6/19 (32%)
		zf-H2C2_2	113..138	CDD:290200	13/24 (54%)
		C2H2 Zn finger	129..149	CDD:275368	8/19 (42%)
		zf-H2C2_2	142..166	CDD:290200	12/23 (52%)
		COG5048	151..>264	CDD:227381	40/114 (35%)
		C2H2 Zn finger	157..177	CDD:275368	11/19 (58%)
		C2H2 Zn finger	185..206	CDD:275368	7/22 (32%)
		C2H2 Zn finger	235..255	CDD:275368	9/19 (47%)
		C2H2 Zn finger	263..285	CDD:275368	9/21 (43%)
		C2H2 Zn finger	293..313	CDD:275368	5/19 (26%)
ZNF841	NP_001356754.1	KRAB	8..69	CDD:214630
		COG5048	260..636	CDD:227381	76/221 (34%)
		C2H2 Zn finger	265..284	CDD:275368
		C2H2 Zn finger	292..312	CDD:275368
		C2H2 Zn finger	320..340	CDD:275368
		C2H2 Zn finger	348..368	CDD:275368
		C2H2 Zn finger	376..396	CDD:275368
		C2H2 Zn finger	404..424	CDD:275368
		C2H2 Zn finger	432..452	CDD:275368	3/11 (27%)
		C2H2 Zn finger	460..480	CDD:275368	3/19 (16%)
		COG5048	484..886	CDD:227381	80/219 (37%)
		C2H2 Zn finger	488..508	CDD:275368	6/19 (32%)
		C2H2 Zn finger	516..536	CDD:275368	8/19 (42%)
		C2H2 Zn finger	544..564	CDD:275368	11/19 (58%)
		C2H2 Zn finger	572..592	CDD:275368	5/19 (26%)
		C2H2 Zn finger	600..620	CDD:275368	9/19 (47%)
		C2H2 Zn finger	628..648	CDD:275368	9/21 (43%)
		C2H2 Zn finger	656..676	CDD:275368	5/19 (26%)
		C2H2 Zn finger	712..732	CDD:275368
		C2H2 Zn finger	740..760	CDD:275368
		C2H2 Zn finger	768..788	CDD:275368
		C2H2 Zn finger	796..816	CDD:275368
		C2H2 Zn finger	824..844	CDD:275368
		C2H2 Zn finger	852..872	CDD:275368
		C2H2 Zn finger	880..900	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.910