DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2120 and Zbtb24

DIOPT Version :9

Sequence 1:NP_572446.2 Gene:CG2120 / 31737 FlyBaseID:FBgn0030005 Length:315 Species:Drosophila melanogaster
Sequence 2:NP_700447.2 Gene:Zbtb24 / 268294 MGIID:3039618 Length:710 Species:Mus musculus


Alignment Length:285 Identity:89/285 - (31%)
Similarity:137/285 - (48%) Gaps:33/285 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly    40 SGERLPMEMELLNPGSEYDLLELVNGALQQRNTTEHKPTDMCKPKRTPTTKRHRTTGKDHTCDIC 104
            |..|:...::|    .:|.||    |....::|.:.    :|..|:       |::|.:..|..|
Mouse   253 SRRRIRRSVKL----KDYKLL----GDEDDQSTAKR----LCGRKK-------RSSGPEARCKDC 298

  Fly   105 DRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFRYANY 169
            ||.|..::.|.||:..||.|:|..|.||||||.|.:.|::|...||.|||:.|.:|||.....:.
Mouse   299 DRVFKYSHFLAIHQRRHTGERPFKCNECGKGFAQKHSLQVHTRMHTGERPYTCTVCGKALTTKHS 363

  Fly   170 LTVHRRLHTGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDPDPEH---------PLAEQEQ 225
            |..|..||:|:|.:.|  ..|...|......:.|.:: |...:.|:..|         .|.:..:
Mouse   364 LLEHMSLHSGQKSFTC--DQCGKYFSQKRQLKSHYRV-HTGHSLPECSHCHRKFMDVSQLKKHLR 425

  Fly   226 RDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRP 290
            ..|....|||.:|.:..|.:..|..|::.|..::.:.|  ..|||.|..:|..:.|.|.||.::|
Mouse   426 THTGEKPFTCEICGKSFTAKSSLQTHIRIHRGEKPYSC--SICGKCFSDSSAKRRHCILHTGKKP 488

  Fly   291 FACPLCPARFLRKSNHKQHLKVHER 315
            |:||.|..:|.|..|.|.|||:|.:
Mouse   489 FSCPECGLQFARLDNLKAHLKIHSK 513

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2120NP_572446.2 C2H2 Zn finger 101..121 CDD:275368 8/19 (42%)
zf-H2C2_2 113..138 CDD:290200 14/24 (58%)
C2H2 Zn finger 129..149 CDD:275368 10/19 (53%)
zf-H2C2_2 142..166 CDD:290200 11/23 (48%)
COG5048 151..>264 CDD:227381 30/121 (25%)
C2H2 Zn finger 157..177 CDD:275368 6/19 (32%)
C2H2 Zn finger 185..206 CDD:275368 4/20 (20%)
C2H2 Zn finger 235..255 CDD:275368 5/19 (26%)
C2H2 Zn finger 263..285 CDD:275368 8/21 (38%)
C2H2 Zn finger 293..313 CDD:275368 10/19 (53%)
Zbtb24NP_700447.2 BTB 27..128 CDD:279045
BTB 38..133 CDD:197585
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 134..176
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 202..256 1/2 (50%)
C2H2 Zn finger 295..315 CDD:275368 8/19 (42%)
zf-H2C2_2 308..332 CDD:290200 14/23 (61%)
COG5048 <320..479 CDD:227381 49/163 (30%)
C2H2 Zn finger 323..343 CDD:275368 10/19 (53%)
zf-H2C2_2 335..360 CDD:290200 11/24 (46%)
C2H2 Zn finger 351..371 CDD:275368 6/19 (32%)
zf-H2C2_2 363..388 CDD:290200 9/26 (35%)
C2H2 Zn finger 379..399 CDD:275368 4/22 (18%)
COG5048 406..>563 CDD:227381 34/110 (31%)
C2H2 Zn finger 407..427 CDD:275368 2/19 (11%)
zf-H2C2_2 420..443 CDD:290200 6/22 (27%)
C2H2 Zn finger 435..455 CDD:275368 5/19 (26%)
zf-H2C2_2 447..471 CDD:290200 7/25 (28%)
C2H2 Zn finger 463..479 CDD:275368 6/17 (35%)
zf-H2C2_2 477..500 CDD:290200 10/22 (45%)
C2H2 Zn finger 491..511 CDD:275368 10/19 (53%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 651..676
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 1 0.950 - 0 Normalized mean entropy S4068
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.950

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