DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2120 and ZNF718

DIOPT Version :9

Sequence 1:NP_572446.2 Gene:CG2120 / 31737 FlyBaseID:FBgn0030005 Length:315 Species:Drosophila melanogaster
Sequence 2:NP_001034216.2 Gene:ZNF718 / 255403 HGNCID:26889 Length:478 Species:Homo sapiens


Alignment Length:235 Identity:71/235 - (30%)
Similarity:119/235 - (50%) Gaps:18/235 - (7%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 KRHRTTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERP 154
            ||.....|.:.|:.|.:.|:.:.:|..||..||.|||::|.:|||.|.|.:.|.:|...|:|::.
Human   218 KRIHAREKFYKCEECGKGFTRSSHLTKHKRIHTGEKPYICEKCGKAFNQSSTLNLHKRIHSAQKY 282

  Fly   155 HKCDICGKGFRYANYLTVHRRLHTGEKPYPC------LATDCHLSFHSIHARRIHT-----KLRH 208
            :||:.|||.|::::.|..|:|:|.||||:.|      ..|....:.|    :||||     |...
Human   283 YKCEECGKAFKWSSSLNEHKRIHAGEKPFSCEECGNVFTTSSDFAKH----KRIHTGEKPYKCEE 343

  Fly   209 AAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFF 273
            ..::. :....|...::..|....:||..|.:.......|::|.:.|..:..:.|  .:|||.|.
Human   344 CGKSF-NRSTTLTTHKRIHTGEKPYTCEECGKAFNWSSTLNVHKRIHSGKNPYKC--EDCGKAFK 405

  Fly   274 SASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHLKVH 313
            ..:.|.:|:..||.::|:.|..|...|.:.|:..:|.|:|
Human   406 VFANLHNHKKIHTGEKPYICKQCGKAFKQSSHLNKHKKIH 445

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2120NP_572446.2 C2H2 Zn finger 101..121 CDD:275368 6/19 (32%)
zf-H2C2_2 113..138 CDD:290200 13/24 (54%)
C2H2 Zn finger 129..149 CDD:275368 8/19 (42%)
zf-H2C2_2 142..166 CDD:290200 10/23 (43%)
COG5048 151..>264 CDD:227381 31/123 (25%)
C2H2 Zn finger 157..177 CDD:275368 8/19 (42%)
C2H2 Zn finger 185..206 CDD:275368 7/31 (23%)
C2H2 Zn finger 235..255 CDD:275368 4/19 (21%)
C2H2 Zn finger 263..285 CDD:275368 7/21 (33%)
C2H2 Zn finger 293..313 CDD:275368 6/19 (32%)
ZNF718NP_001034216.2 KRAB 4..64 CDD:214630
C2H2 Zn finger 146..165 CDD:275368
C2H2 Zn finger 173..193 CDD:275368
C2H2 Zn finger 201..221 CDD:275368 2/2 (100%)
COG5048 <225..386 CDD:227381 50/165 (30%)
C2H2 Zn finger 229..249 CDD:275368 6/19 (32%)
C2H2 Zn finger 257..277 CDD:275368 8/19 (42%)
C2H2 Zn finger 285..305 CDD:275368 8/19 (42%)
C2H2 Zn finger 313..333 CDD:275368 4/23 (17%)
COG5048 <322..474 CDD:227381 32/131 (24%)
C2H2 Zn finger 341..361 CDD:275368 1/20 (5%)
C2H2 Zn finger 369..389 CDD:275368 4/19 (21%)
C2H2 Zn finger 397..417 CDD:275368 7/21 (33%)
C2H2 Zn finger 425..445 CDD:275368 6/19 (32%)
C2H2 Zn finger 453..473 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.000

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