DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2120 and Zfp958

DIOPT Version :9

Sequence 1:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001355333.1	Gene:	Zfp958 / 233987	MGIID:	2385298	Length:	489	Species:	Mus musculus

Alignment Length:	267	Identity:	89/267 - (33%)
Similarity:	123/267 - (46%)	Gaps:	38/267 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    55 SEYDLLELVNGALQQRNTTEHKPTDMCKP-----KRTPTTKRHRTT---GKDHTCDICDRRFSEA 111
            ||::.|:     ..:|..:|.||.: |..     ......:.|..|   .|.:.|:.||:.||:.
Mouse   163 SEHNTLQ-----KHKRTHSEEKPYE-CNQCGKAFAHHNILRNHERTHIGEKPYQCNECDKAFSQH 221

  Fly   112 YNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRL 176
            |.|||||..||.|||:.|.:|.|.|..|:.||:|..|||.|:|:||:.|||.|...:.|..|:|.
Mouse   222 YYLRIHKRIHTGEKPYECNQCDKAFACLSYLRVHGRTHTGEKPYKCNQCGKVFASHSNLKRHKRT 286

  Fly   177 HTGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRV 241
            |||||||.|  ..|..:|...|..|||                    |:..|....|.|..|.:.
Mouse   287 HTGEKPYEC--NQCGKAFSDHHTLRIH--------------------ERAHTGEKPFECNQCGKT 329

  Fly   242 LTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNH 306
            ......|.||.:.|..::...|.|  |||.|...|..:.|:..||.::|:.|..|...|...|..
Mouse   330 FKLHSQLRIHKRTHTGEKPHECNQ--CGKTFACPSSFQKHKRIHTGEKPYECNQCLKAFAYHSRL 392

  Fly   307 KQHLKVH 313
            ::|.:.|
Mouse   393 RKHERTH 399

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	11/19 (58%)
		zf-H2C2_2	113..138	CDD:290200	14/24 (58%)
		C2H2 Zn finger	129..149	CDD:275368	8/19 (42%)
		zf-H2C2_2	142..166	CDD:290200	14/23 (61%)
		COG5048	151..>264	CDD:227381	34/112 (30%)
		C2H2 Zn finger	157..177	CDD:275368	8/19 (42%)
		C2H2 Zn finger	185..206	CDD:275368	7/20 (35%)
		C2H2 Zn finger	235..255	CDD:275368	5/19 (26%)
		C2H2 Zn finger	263..285	CDD:275368	8/21 (38%)
		C2H2 Zn finger	293..313	CDD:275368	5/19 (26%)
Zfp958	NP_001355333.1	KRAB	26..66	CDD:334504
		C2H2 Zn finger	103..119	CDD:275368
		COG5048	125..484	CDD:227381	89/267 (33%)
		C2H2 Zn finger	127..147	CDD:275368
		C2H2 Zn finger	155..175	CDD:275368	4/16 (25%)
		C2H2 Zn finger	183..203	CDD:275368	2/19 (11%)
		C2H2 Zn finger	211..231	CDD:275368	11/19 (58%)
		C2H2 Zn finger	239..259	CDD:275368	8/19 (42%)
		C2H2 Zn finger	267..287	CDD:275368	8/19 (42%)
		C2H2 Zn finger	295..315	CDD:275368	8/41 (20%)
		C2H2 Zn finger	323..343	CDD:275368	5/19 (26%)
		C2H2 Zn finger	351..371	CDD:275368	8/21 (38%)
		C2H2 Zn finger	379..399	CDD:275368	5/19 (26%)
		C2H2 Zn finger	407..427	CDD:275368
		C2H2 Zn finger	435..455	CDD:275368
		C2H2 Zn finger	463..483	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000