DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2120 and Zfp114

DIOPT Version :9

Sequence 1:NP_572446.2 Gene:CG2120 / 31737 FlyBaseID:FBgn0030005 Length:315 Species:Drosophila melanogaster
Sequence 2:NP_001025104.2 Gene:Zfp114 / 232966 MGIID:3037815 Length:585 Species:Mus musculus


Alignment Length:294 Identity:97/294 - (32%)
Similarity:138/294 - (46%) Gaps:41/294 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly    33 FAQLEDLS------GERLPMEMELLNPGSEYDLLELVNGALQQRNTTEHKP---TDMCK----PK 84
            |::..||:      .|..|.:.|:...|    ..:|.:....:|..|..||   .|..|    ..
Mouse   315 FSRTSDLNIHCRVHTEEKPHKCEVCGKG----FTKLSHLQAHERIHTGEKPYKCGDCGKRFSCSS 375

  Fly    85 RTPTTKRHRTTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTH 149
            ...|.:|..|..|.:.||.|.:|||.::||..|:..||.|||:.|.||||||...:..:.|...|
Mouse   376 NLHTHQRVHTEEKPYKCDECGKRFSLSFNLHSHQRVHTGEKPYKCEECGKGFTSASSFQSHQRVH 440

  Fly   150 TAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDP 214
            |.|:|..|.:|||||...:||..|:|:|||||||.|  ..|..:|    ::|.|..:.....|..
Mouse   441 TGEKPFVCSVCGKGFSRTSYLQTHQRVHTGEKPYQC--DSCGKAF----SQRSHLLVHQIIHTGE 499

  Fly   215 DPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELK 279
            .|                |.|..|.:..|....||||.:.|..::.:.|.|  |||.|..||..:
Mouse   500 KP----------------FKCEECGKEFTQSTGLSIHQRVHTGEKPYTCQQ--CGKGFSQASHFQ 546

  Fly   280 HHQIAHTQQRPFACPLCPARFLRKSNHKQHLKVH 313
            .||..||:::|:.|.:|...|.::|:...|.:||
Mouse   547 RHQRVHTKEKPYICGICCKGFSQRSHLVYHQRVH 580

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2120NP_572446.2 C2H2 Zn finger 101..121 CDD:275368 9/19 (47%)
zf-H2C2_2 113..138 CDD:290200 15/24 (63%)
C2H2 Zn finger 129..149 CDD:275368 8/19 (42%)
zf-H2C2_2 142..166 CDD:290200 11/23 (48%)
COG5048 151..>264 CDD:227381 35/112 (31%)
C2H2 Zn finger 157..177 CDD:275368 10/19 (53%)
C2H2 Zn finger 185..206 CDD:275368 5/20 (25%)
C2H2 Zn finger 235..255 CDD:275368 7/19 (37%)
C2H2 Zn finger 263..285 CDD:275368 10/21 (48%)
C2H2 Zn finger 293..313 CDD:275368 5/19 (26%)
Zfp114NP_001025104.2 KRAB 8..48 CDD:366587
C2H2 Zn finger 281..300 CDD:275368
C2H2 Zn finger 308..328 CDD:275368 3/12 (25%)
zf-H2C2_2 320..345 CDD:372612 6/28 (21%)
C2H2 Zn finger 336..356 CDD:275368 4/23 (17%)
COG5048 <344..585 CDD:227381 90/261 (34%)
C2H2 Zn finger 364..384 CDD:275368 4/19 (21%)
C2H2 Zn finger 392..412 CDD:275368 9/19 (47%)
C2H2 Zn finger 420..440 CDD:275368 8/19 (42%)
C2H2 Zn finger 448..468 CDD:275368 10/19 (53%)
C2H2 Zn finger 476..496 CDD:275368 5/25 (20%)
C2H2 Zn finger 504..524 CDD:275368 7/19 (37%)
C2H2 Zn finger 532..552 CDD:275368 10/21 (48%)
C2H2 Zn finger 560..580 CDD:275368 5/19 (26%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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