DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2120 and Zfp62

DIOPT Version :9

Sequence 1:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001349654.1	Gene:	Zfp62 / 22720	MGIID:	99662	Length:	914	Species:	Mus musculus

Alignment Length:	273	Identity:	84/273 - (30%)
Similarity:	118/273 - (43%)	Gaps:	62/273 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 KRHRTTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGF----RQLNKLRI------ 144
            ||..|..|.:.||.|.:.||.:..||:||..||.|||:.|.||||.|    ..||...|
Mouse   262 KRIHTGEKPYECDTCGKTFSNSSGLRVHKRIHTGEKPYECDECGKAFITCRTLLNHKSIHFGDKP 326

  Fly   145 ------------------HAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDCH 191
                              |.|.||.|:|::||.|||.||.::.|.||:|:|||||||.|  ..|.
Mouse   327 YKCDECEKSFNYSSLLIQHKVIHTGEKPYECDECGKAFRNSSGLIVHKRIHTGEKPYKC--DICG 389

  Fly   192 LSFHSIHARRIHTKLRHAAQTDPDPEHP-------------------LAEQEQRDTSALSFTCPV 237
            .:|.......:|..:           ||                   |.:.:...|....:.|.|
Mouse   390 KAFSYSSGLAVHKSI-----------HPGKKAHECKDCGKSFSYNSLLLQHKTIHTGERPYVCDV 443

  Fly   238 CSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLR 302
            |.:...:...|.:|.:.|..::.:.|  ..|||.:.|.|.||:|:..|..::|:.|..|...|..
Mouse   444 CGKTFRNNSGLKVHRRLHTGEKPYKC--DVCGKAYISRSSLKNHKGIHMGEKPYKCSYCEKSFNY 506

  Fly   303 KSNHKQHLKVHER 315
            .|..:||.::|.|
Mouse   507 SSALEQHKRIHTR 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	9/19 (47%)
		zf-H2C2_2	113..138	CDD:290200	15/28 (54%)
		C2H2 Zn finger	129..149	CDD:275368	11/47 (23%)
		zf-H2C2_2	142..166	CDD:290200	13/47 (28%)
		COG5048	151..>264	CDD:227381	34/131 (26%)
		C2H2 Zn finger	157..177	CDD:275368	11/19 (58%)
		C2H2 Zn finger	185..206	CDD:275368	4/20 (20%)
		C2H2 Zn finger	235..255	CDD:275368	5/19 (26%)
		C2H2 Zn finger	263..285	CDD:275368	9/21 (43%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
Zfp62	NP_001349654.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..35
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	80..101
		COG5048	127..542	CDD:227381	84/273 (31%)
		C2H2 Zn finger	133..153	CDD:275368
		C2H2 Zn finger	161..181	CDD:275368
		C2H2 Zn finger	189..209	CDD:275368
		C2H2 Zn finger	217..237	CDD:275368
		C2H2 Zn finger	245..265	CDD:275368	2/2 (100%)
		C2H2 Zn finger	273..293	CDD:275368	9/19 (47%)
		C2H2 Zn finger	301..321	CDD:275368	8/19 (42%)
		C2H2 Zn finger	329..349	CDD:275368	2/19 (11%)
		C2H2 Zn finger	357..377	CDD:275368	11/19 (58%)
		SFP1	<379..458	CDD:227516	17/91 (19%)
		C2H2 Zn finger	385..405	CDD:275368	4/32 (13%)
		C2H2 Zn finger	413..433	CDD:275368	1/19 (5%)
		COG5048	437..850	CDD:227381	25/85 (29%)
		C2H2 Zn finger	441..461	CDD:275368	5/19 (26%)
		C2H2 Zn finger	469..489	CDD:275368	9/21 (43%)
		C2H2 Zn finger	497..517	CDD:275368	6/19 (32%)
		C2H2 Zn finger	525..545	CDD:275368
		C2H2 Zn finger	553..573	CDD:275368
		C2H2 Zn finger	581..601	CDD:275368
		C2H2 Zn finger	609..629	CDD:275368
		C2H2 Zn finger	637..657	CDD:275368
		C2H2 Zn finger	665..685	CDD:275368
		C2H2 Zn finger	693..713	CDD:275368
		C2H2 Zn finger	721..741	CDD:275368
		C2H2 Zn finger	749..769	CDD:275368
		C2H2 Zn finger	777..797	CDD:275368
		C2H2 Zn finger	805..824	CDD:275368
		C2H2 Zn finger	832..852	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000