DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2120 and Zbtb17

DIOPT Version :9

Sequence 1:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_001365755.1	Gene:	Zbtb17 / 22642	MGIID:	107410	Length:	819	Species:	Mus musculus

Alignment Length:	278	Identity:	86/278 - (30%)
Similarity:	126/278 - (45%)	Gaps:	33/278 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    40 SGERLPMEMELLNPGSEYDLLELVNGALQQRNTTEHKPTDMCKP-KRTPTTKRH---RTTGKDHT 100
            ||:.|.||.:.|..|:..|..|     .:...:..||..|..|. ..|...|||   .|..|..:
Mouse   292 SGQELGMEGQNLRSGTYGDRTE-----SKAYGSIIHKCEDCGKEFTHTGNFKRHIRIHTGEKPFS 351

  Fly   101 CDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFR 165
            |..|.:.||:....:.|:.||:..||:.|.||||.:|.::.|.:|...|:.|..::|..|||.|.
Mouse   352 CRECSKAFSDPAACKAHEKTHSPLKPYGCEECGKSYRLISLLNLHKKRHSGEARYRCGDCGKLFT 416

  Fly   166 YANYLTVHRRLHTGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDPDPEHPLAEQEQRDTSA 230
            .:..|..|:.:|:|:|||.|  ..|..||..     ..:|:||....|.|.||
Mouse   417 TSGNLKRHQLVHSGQKPYQC--DYCGRSFSD-----PTSKMRHLETHDTDKEH------------ 462

  Fly   231 LSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPL 295
               .||.|.:.......|..|||.|.  .|.|....||||:|.::..||.|...|:.::|:.|..
Mouse   463 ---KCPHCDKKFNQVGNLKAHLKIHI--ADGPLKCRECGKQFTTSGNLKRHLRIHSGEKPYVCTH 522

  Fly   296 CPARFLRKSNHKQHLKVH 313
            |..:|......::|:::|
Mouse   523 CQRQFADPGALQRHVRIH 540

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	5/19 (26%)
		zf-H2C2_2	113..138	CDD:290200	10/24 (42%)
		C2H2 Zn finger	129..149	CDD:275368	8/19 (42%)
		zf-H2C2_2	142..166	CDD:290200	9/23 (39%)
		COG5048	151..>264	CDD:227381	34/112 (30%)
		C2H2 Zn finger	157..177	CDD:275368	7/19 (37%)
		C2H2 Zn finger	185..206	CDD:275368	4/20 (20%)
		C2H2 Zn finger	235..255	CDD:275368	7/19 (37%)
		C2H2 Zn finger	263..285	CDD:275368	8/21 (38%)
		C2H2 Zn finger	293..313	CDD:275368	4/19 (21%)
Zbtb17	NP_001365755.1	BTB_POZ_ZBTB17_MIZ1	2..113	CDD:349515
		PRK07003	<115..>266	CDD:235906
		COG5048	322..653	CDD:227381	77/243 (32%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	352..372	CDD:275368	5/19 (26%)
		C2H2 Zn finger	380..400	CDD:275368	8/19 (42%)
		C2H2 Zn finger	408..428	CDD:275368	7/19 (37%)
		C2H2 Zn finger	436..456	CDD:275368	7/26 (27%)
		C2H2 Zn finger	464..484	CDD:275368	7/19 (37%)
		C2H2 Zn finger	492..512	CDD:275368	8/19 (42%)
		C2H2 Zn finger	520..540	CDD:275368	4/19 (21%)
		C2H2 Zn finger	548..568	CDD:275368
		C2H2 Zn finger	576..596	CDD:275368
		C2H2 Zn finger	604..624	CDD:275368
		C2H2 Zn finger	632..651	CDD:275370
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100