DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2120 and Zfp160

DIOPT Version :9

Sequence 1:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster
Sequence 2:	NP_663458.2	Gene:	Zfp160 / 224585	MGIID:	108187	Length:	650	Species:	Mus musculus

Alignment Length:	226	Identity:	80/226 - (35%)
Similarity:	110/226 - (48%)	Gaps:	28/226 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 KRHRTTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERP 154
            :||.|..|.:.|:.|.:.||:..:|:.|:..||.|||..|..|||.|...:.|..|.|.||.::|
Mouse   193 ERHHTGAKPYKCNECGKVFSQNSHLKSHRRIHTGEKPFKCNHCGKAFSVRSNLTHHQVIHTGDKP 257

  Fly   155 HKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDCHLSFHSIHARRIHTKL--RHAAQTDPDPE 217
            :||:.|||.|...:.||:|||.|||||||.|  .:|...|.|      |:.|  ..|..|...|
Mouse   258 YKCNECGKVFSQTSSLTIHRRTHTGEKPYRC--NECGKVFSS------HSNLNTHQAIHTGEKP- 313

  Fly   218 HPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQ 282
                           :.|..|.:|.|...:|:.|.:.|..::.:.|  .||||.|...|.|..||
Mouse   314 ---------------YKCSECGKVFTQNSHLANHWRIHTGEKPYKC--NECGKAFSVYSSLTTHQ 361

  Fly   283 IAHTQQRPFACPLCPARFLRKSNHKQHLKVH 313
            ..||.::|:.|..|...|.:.|:...|..||
Mouse   362 AIHTGEKPYKCNECGKVFTQNSHLASHRGVH 392

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	6/19 (32%)
		zf-H2C2_2	113..138	CDD:290200	12/24 (50%)
		C2H2 Zn finger	129..149	CDD:275368	8/19 (42%)
		zf-H2C2_2	142..166	CDD:290200	12/23 (52%)
		COG5048	151..>264	CDD:227381	35/114 (31%)
		C2H2 Zn finger	157..177	CDD:275368	10/19 (53%)
		C2H2 Zn finger	185..206	CDD:275368	5/20 (25%)
		C2H2 Zn finger	235..255	CDD:275368	6/19 (32%)
		C2H2 Zn finger	263..285	CDD:275368	10/21 (48%)
		C2H2 Zn finger	293..313	CDD:275368	5/19 (26%)
Zfp160	NP_663458.2	KRAB	8..68	CDD:214630
		KRAB	8..47	CDD:279668
		C2H2 Zn finger	148..168	CDD:275368
		C2H2 Zn finger	176..196	CDD:275368	1/2 (50%)
		zf-H2C2_2	188..213	CDD:290200	7/19 (37%)
		COG5048	200..635	CDD:227381	77/219 (35%)
		zf-C2H2	202..224	CDD:278523	6/21 (29%)
		C2H2 Zn finger	204..224	CDD:275368	6/19 (32%)
		zf-H2C2_2	216..240	CDD:290200	11/23 (48%)
		C2H2 Zn finger	232..252	CDD:275368	8/19 (42%)
		zf-H2C2_2	244..269	CDD:290200	12/24 (50%)
		C2H2 Zn finger	260..280	CDD:275368	10/19 (53%)
		zf-H2C2_2	272..297	CDD:290200	15/26 (58%)
		C2H2 Zn finger	288..308	CDD:275368	7/27 (26%)
		zf-H2C2_2	300..325	CDD:290200	7/40 (18%)
		C2H2 Zn finger	316..336	CDD:275368	6/19 (32%)
		C2H2 Zn finger	344..364	CDD:275368	10/21 (48%)
		zf-H2C2_2	356..381	CDD:290200	9/24 (38%)
		C2H2 Zn finger	372..392	CDD:275368	5/19 (26%)
		zf-H2C2_2	384..409	CDD:290200	3/9 (33%)
		C2H2 Zn finger	400..420	CDD:275368
		zf-H2C2_2	412..436	CDD:290200
		C2H2 Zn finger	428..448	CDD:275368
		zf-H2C2_2	440..465	CDD:290200
		C2H2 Zn finger	456..476	CDD:275368
		zf-H2C2_2	468..493	CDD:290200
		C2H2 Zn finger	484..504	CDD:275368
		zf-H2C2_2	496..521	CDD:290200
		C2H2 Zn finger	512..532	CDD:275368
		zf-H2C2_2	524..548	CDD:290200
		C2H2 Zn finger	540..560	CDD:275368
		zf-H2C2_2	552..577	CDD:290200
		C2H2 Zn finger	568..588	CDD:275368
		zf-H2C2_2	580..604	CDD:290200
		C2H2 Zn finger	596..616	CDD:275368
		zf-H2C2_2	608..633	CDD:290200
		C2H2 Zn finger	624..644	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000