DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2120 and ZNF431

DIOPT Version :9

Sequence 1:NP_572446.2 Gene:CG2120 / 31737 FlyBaseID:FBgn0030005 Length:315 Species:Drosophila melanogaster
Sequence 2:XP_011526052.1 Gene:ZNF431 / 170959 HGNCID:20809 Length:593 Species:Homo sapiens


Alignment Length:233 Identity:74/233 - (31%)
Similarity:115/233 - (49%) Gaps:14/233 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly    90 KRHRTTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERP 154
            ||..|..|...|:.|.:.|.::..|..||:.||.|||:.|.||||.|.:.:.|..|.:.||.|:|
Human   268 KRIHTGEKPFKCEECGKAFKQSSTLTTHKIIHTGEKPYRCEECGKAFNRSSHLTTHKIIHTGEKP 332

  Fly   155 HKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDPDPEH- 218
            :||:.|||.|..::.|:.|:.:|.|||||.|  .:|..:|:.......| |:.|..:.....|. 
Human   333 YKCEECGKAFNQSSTLSTHKFIHAGEKPYKC--EECDKAFNRFSYLTKH-KIIHTGEKSYKCEEC 394

  Fly   219 --------PLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSA 275
                    .|.:.::..|....:.|.||.:...:...|:.|...|..::.:.|  .||||.|..:
Human   395 GKGFNWSSTLTKHKRIHTGEKPYKCEVCGKAFNESSNLTTHKMIHTGEKPYKC--EECGKAFNRS 457

  Fly   276 SELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHLKVH 313
            .:|..|:|.||.::|:.|..|...|.:.|....|.::|
Human   458 PQLTAHKIIHTGEKPYKCEECGKAFSQSSILTTHKRIH 495

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2120NP_572446.2 C2H2 Zn finger 101..121 CDD:275368 6/19 (32%)
zf-H2C2_2 113..138 CDD:290200 14/24 (58%)
C2H2 Zn finger 129..149 CDD:275368 8/19 (42%)
zf-H2C2_2 142..166 CDD:290200 12/23 (52%)
COG5048 151..>264 CDD:227381 31/121 (26%)
C2H2 Zn finger 157..177 CDD:275368 7/19 (37%)
C2H2 Zn finger 185..206 CDD:275368 4/20 (20%)
C2H2 Zn finger 235..255 CDD:275368 5/19 (26%)
C2H2 Zn finger 263..285 CDD:275368 9/21 (43%)
C2H2 Zn finger 293..313 CDD:275368 5/19 (26%)
ZNF431XP_011526052.1 KRAB 51..112 CDD:214630
KRAB 51..90 CDD:279668
zf-H2C2_2 209..230 CDD:290200
COG5048 218..570 CDD:227381 74/233 (32%)
C2H2 Zn finger 223..243 CDD:275368
C2H2 Zn finger 251..271 CDD:275368 2/2 (100%)
zf-H2C2_2 264..288 CDD:290200 7/19 (37%)
C2H2 Zn finger 279..299 CDD:275368 6/19 (32%)
zf-H2C2_2 292..316 CDD:290200 14/23 (61%)
C2H2 Zn finger 307..327 CDD:275368 8/19 (42%)
zf-H2C2_2 319..344 CDD:290200 12/24 (50%)
C2H2 Zn finger 335..355 CDD:275368 7/19 (37%)
C2H2 Zn finger 363..383 CDD:275368 5/22 (23%)
zf-H2C2_2 375..399 CDD:290200 4/24 (17%)
C2H2 Zn finger 391..411 CDD:275368 2/19 (11%)
zf-H2C2_2 404..427 CDD:290200 5/22 (23%)
C2H2 Zn finger 419..439 CDD:275368 5/19 (26%)
zf-H2C2_2 431..456 CDD:290200 9/26 (35%)
C2H2 Zn finger 447..467 CDD:275368 9/21 (43%)
zf-H2C2_2 460..484 CDD:290200 9/23 (39%)
C2H2 Zn finger 475..495 CDD:275368 5/19 (26%)
zf-H2C2_2 488..512 CDD:290200 2/8 (25%)
C2H2 Zn finger 503..523 CDD:275368
zf-H2C2_2 515..540 CDD:290200
C2H2 Zn finger 531..551 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.910

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