DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2120 and ZNF565

DIOPT Version :9

Sequence 1:NP_572446.2 Gene:CG2120 / 31737 FlyBaseID:FBgn0030005 Length:315 Species:Drosophila melanogaster
Sequence 2:NP_001035939.1 Gene:ZNF565 / 147929 HGNCID:26726 Length:499 Species:Homo sapiens


Alignment Length:271 Identity:95/271 - (35%)
Similarity:132/271 - (48%) Gaps:41/271 - (15%)


- Green bases have known domain annotations that are detailed below.


  Fly    69 QRNTTEHKPTDMCKP-----KRTPTTKRHRT--TG-KDHTCDICDRRFSEAYNLRIHKMTHTDEK 125
            ||..|..||.| ||.     .||.....|:.  || |.:.|..|.:.|.:...|.:|:.|||.||
Human   214 QRIHTGEKPYD-CKDCGKAFGRTSELILHQRLHTGVKPYECKECGKTFRQHSQLILHQRTHTGEK 277

  Fly   126 PHVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDC 190
            |:||.:|||.|.:.::|.:|...||..||::|..|||.||..:.||||:|:|||||||.|  .:|
Human   278 PYVCKDCGKAFIRGSQLTVHRRIHTGARPYECKECGKAFRQHSQLTVHQRIHTGEKPYEC--KEC 340

  Fly   191 HLSFHSIHA------RRIHT------------KLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPV 237
            ...|  ||:      :|||:            ..|..||        |...::..|....:.|..
Human   341 GKGF--IHSSEVTRHQRIHSGEKPYECKECGKAFRQHAQ--------LTRHQRVHTGDRPYECKD 395

  Fly   238 CSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLR 302
            |.:..:...||..|.:.|...:.:.|  .||||.|...|:|.|||..||.::|:.|..|...|:|
Human   396 CGKAFSRSSYLIQHQRIHTGDKPYEC--KECGKAFIRVSQLTHHQRIHTCEKPYECRECGMAFIR 458

  Fly   303 KSNHKQHLKVH 313
            .|...:|.::|
Human   459 SSQLTEHQRIH 469

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2120NP_572446.2 C2H2 Zn finger 101..121 CDD:275368 5/19 (26%)
zf-H2C2_2 113..138 CDD:290200 14/24 (58%)
C2H2 Zn finger 129..149 CDD:275368 7/19 (37%)
zf-H2C2_2 142..166 CDD:290200 11/23 (48%)
COG5048 151..>264 CDD:227381 39/130 (30%)
C2H2 Zn finger 157..177 CDD:275368 11/19 (58%)
C2H2 Zn finger 185..206 CDD:275368 8/38 (21%)
C2H2 Zn finger 235..255 CDD:275368 5/19 (26%)
C2H2 Zn finger 263..285 CDD:275368 11/21 (52%)
C2H2 Zn finger 293..313 CDD:275368 6/19 (32%)
ZNF565NP_001035939.1 KRAB 6..66 CDD:214630
C2H2 Zn finger 169..189 CDD:275368
COG5048 193..498 CDD:227381 95/271 (35%)
C2H2 Zn finger 197..217 CDD:275368 2/2 (100%)
C2H2 Zn finger 225..245 CDD:275368 5/19 (26%)
C2H2 Zn finger 253..273 CDD:275368 5/19 (26%)
C2H2 Zn finger 281..301 CDD:275368 7/19 (37%)
C2H2 Zn finger 309..329 CDD:275368 11/19 (58%)
C2H2 Zn finger 337..357 CDD:275368 6/23 (26%)
C2H2 Zn finger 365..385 CDD:275368 4/27 (15%)
C2H2 Zn finger 393..413 CDD:275368 5/19 (26%)
C2H2 Zn finger 421..441 CDD:275368 11/21 (52%)
C2H2 Zn finger 449..469 CDD:275368 6/19 (32%)
C2H2 Zn finger 477..497 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
00.000

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