DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2120 and ZNF420

DIOPT Version :9

Sequence 1:NP_572446.2 Gene:CG2120 / 31737 FlyBaseID:FBgn0030005 Length:315 Species:Drosophila melanogaster
Sequence 2:NP_001316444.1 Gene:ZNF420 / 147923 HGNCID:20649 Length:704 Species:Homo sapiens


Alignment Length:351 Identity:103/351 - (29%)
Similarity:147/351 - (41%) Gaps:87/351 - (24%)


- Green bases have known domain annotations that are detailed below.


  Fly    24 DVCLEDLQLFAQLE--------DLSGERLPMEMEL-------------LNPGSEYDLLELVNGAL 67
            ||.||:......|:        |||.|:...|.||             |...:..|.|| ..|.:
Human    33 DVMLENYSNLVSLDLPSRCASKDLSPEKNTYETELSQWEMSDRLENCDLEESNSRDYLE-AKGKM 96

  Fly    68 --QQRNTTEH------------------------------KPTDMCKP-----KRTPTTKRHRT- 94
              ||.|..|:                              ||. .||.     :|.....:|:: 
Human    97 EKQQENQKEYFRQGMIIYDKMSIFNQHTYLSQHSRCHSTEKPY-KCKECGKAFRRASHLTQHQSI 160

  Fly    95 -TG-KDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERPHKC 157
             || |.:.|..|.:.||....|.:|:..||.|||:.|.||||.|.|.::|.:|...||.|:|:||
Human   161 HTGEKPYECKQCGKAFSRDSQLSLHQRLHTGEKPYACKECGKAFTQSSQLILHHRIHTGEKPYKC 225

  Fly   158 DICGKGFRYANYLTVHRRLHTGEKPYPCLATDCHLSFHSIHARRIHTKLRHAAQTDPDPEHPLAE 222
            :.|||.|..::.||.|:::|||||||.|  .:|..:|.......:|.:|.               
Human   226 EECGKAFIRSSQLTRHQKVHTGEKPYEC--KECGKAFTQNSQLTLHQRLH--------------- 273

  Fly   223 QEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQ 287
                 |....:.|..|.:|.|....|.:|.:.|..::.:.|  .||||.|...|:|..||..|..
Human   274 -----TGEKLYECKECRKVFTQLSQLILHKRIHTGEKPYEC--KECGKAFICGSQLSQHQKIHNG 331

  Fly   288 QRPFACPLCPARFLRKSNHKQHLKVH 313
            ::|:.|..|...|:|.|...||.::|
Human   332 EKPYECKECGRAFIRGSLLMQHQRIH 357

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2120NP_572446.2 C2H2 Zn finger 101..121 CDD:275368 6/19 (32%)
zf-H2C2_2 113..138 CDD:290200 13/24 (54%)
C2H2 Zn finger 129..149 CDD:275368 9/19 (47%)
zf-H2C2_2 142..166 CDD:290200 12/23 (52%)
COG5048 151..>264 CDD:227381 31/112 (28%)
C2H2 Zn finger 157..177 CDD:275368 8/19 (42%)
C2H2 Zn finger 185..206 CDD:275368 4/20 (20%)
C2H2 Zn finger 235..255 CDD:275368 6/19 (32%)
C2H2 Zn finger 263..285 CDD:275368 10/21 (48%)
C2H2 Zn finger 293..313 CDD:275368 7/19 (37%)
ZNF420NP_001316444.1 None


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 1 1.000 - -
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.000

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