Protein Alignment CG2120 and ZNF573

DIOPT Version :9

• Sequence 1: NP_572446.2
• Gene: CG2120 / 31737
• FlyBaseID: FBgn0030005
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_001166161.1
• Gene: ZNF573 / 126231
• HGNCID: 26420
• Length: 665
• Species: Homo sapiens
• Alignment Length: 229
• Identity: 81/229 - (35%)
• Similarity: 112/229 - (48%)
• Gaps: 34/229 - (14%)

  Fly    90 KRHRTTGKDHTCDICDRRFSEAYNLRIHKMTHTDEKPHVCVECGKGFRQLNKLRIHAVTHTAERP 154
            :|..|.||.:.|..|.|.||:..:||||:..||.|||:.|.||||.|.:.:.|..|...||.|:|
Human   237 ERIHTGGKPYECQECGRAFSQGGHLRIHQRVHTGEKPYKCKECGKTFSRRSNLVEHGQFHTDEKP 301

  Fly   155 HKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATDC-----HLSFHSIHARRIHTKLRHAAQTDP 214
            :.|:.|||.||..:.||||:|:|||:|||.|  .:|     ..|:..:| :|||
Human   302 YICEKCGKAFRRGHQLTVHQRVHTGKKPYEC--KECGKGYTTASYFLLH-QRIH----------- 352

  Fly   215 DPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRHYNQRDFPCPQPECGKRFFSASELK 279
                         .....:.|..|.:..|....|:.|...|..::.|.|.|  |||.:.:.|:|.
Human   353 -------------KGGKPYECKECKKTFTLYRNLTRHQNIHTGEKLFECKQ--CGKTYTTGSKLF 402

  Fly   280 HHQIAHTQQRPFACPLCPARFLRKSNHKQHLKVH 313
            .||..||.::|:.|..|...|......|||.|:|
Human   403 QHQKTHTGEKPYECKECGKAFSLYGYLKQHQKIH 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	9/19 (47%)
		zf-H2C2_2	113..138	CDD:290200	15/24 (63%)
		C2H2 Zn finger	129..149	CDD:275368	8/19 (42%)
		zf-H2C2_2	142..166	CDD:290200	11/23 (48%)
		COG5048	151..>264	CDD:227381	33/117 (28%)
		C2H2 Zn finger	157..177	CDD:275368	11/19 (58%)
		C2H2 Zn finger	185..206	CDD:275368	7/25 (28%)
		C2H2 Zn finger	235..255	CDD:275368	5/19 (26%)
		C2H2 Zn finger	263..285	CDD:275368	9/21 (43%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)
ZNF573	NP_001166161.1	KRAB	28..89	CDD:214630
		KRAB	28..67	CDD:279668
		C2H2 Zn finger	136..156	CDD:275368
		C2H2 Zn finger	164..184	CDD:275368
		C2H2 Zn finger	192..212	CDD:275368
		C2H2 Zn finger	220..240	CDD:275368	1/2 (50%)
		COG5048	244..628	CDD:227381	78/222 (35%)
		C2H2 Zn finger	248..268	CDD:275368	9/19 (47%)
		zf-H2C2_2	260..285	CDD:290200	15/24 (63%)
		C2H2 Zn finger	276..292	CDD:275368	7/15 (47%)
		C2H2 Zn finger	304..324	CDD:275368	11/19 (58%)
		C2H2 Zn finger	332..352	CDD:275368	5/22 (23%)
		C2H2 Zn finger	360..380	CDD:275368	5/19 (26%)
		C2H2 Zn finger	388..408	CDD:275368	9/21 (43%)
		zf-H2C2_2	401..424	CDD:290200	8/22 (36%)
		C2H2 Zn finger	416..436	CDD:275368	7/19 (37%)
		C2H2 Zn finger	444..464	CDD:275368
		C2H2 Zn finger	472..492	CDD:275368
		zf-H2C2_2	484..508	CDD:290200
		C2H2 Zn finger	500..520	CDD:275368
		zf-H2C2_2	512..536	CDD:290200
		C2H2 Zn finger	528..548	CDD:275368
		C2H2 Zn finger	556..576	CDD:275368
		C2H2 Zn finger	584..604	CDD:275368
		zf-H2C2_2	596..621	CDD:290200
		C2H2 Zn finger	612..632	CDD:275368
		zf-H2C2_2	624..649	CDD:290200
		C2H2 Zn finger	640..660	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000