Protein Alignment CG2120 and ZNF257

DIOPT Version :9

• Sequence 1: NP_572446.2
• Gene: CG2120 / 31737
• FlyBaseID: FBgn0030005
• Length: 315
• Species: Drosophila melanogaster
• Sequence 2: NP_258429.2
• Gene: ZNF257 / 113835
• HGNCID: 13498
• Length: 563
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 83/263 - (31%)
• Similarity: 121/263 - (46%)
• Gaps: 45/263 - (17%)

  Fly    70 RNTTEHKPTDMCKPKRTPTT----------KRHRTTGKDHTCDICDRRFSEAYNLRIHKMTHTDE 124
            |:...|.....||.|....:          ||.......|.|:.|.:.|:::..|..||||||.|
Human   162 RHKIRHTEKKTCKCKECGKSFCMLSQLTRHKRIHIRENSHKCEECGKAFNQSSALTRHKMTHTGE 226

  Fly   125 KPHVCVECGKGFRQLNKLRIHAVTHTAERPHKCDICGKGFRYANYLTVHRRLHTGEKPYPCLATD 189
            ||:.|.||||.|.:.:.|..|.|.||.|:|:||:.|||.|..::::|.|:|:|..|||:.  ..:
Human   227 KPYKCEECGKAFNRSSHLTQHKVIHTREKPYKCEECGKAFNRSSHITQHKRIHNREKPFK--YDE 289

  Fly   190 CHLSFHSIHA-------RRIHTKLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCY 247
            |..:|....|       :||||           .|.|             :.|..|.:.......
Human   290 CCKAFKWSSALTTLTQHKRIHT-----------GEKP-------------YKCEECGKAFNQSSA 330

  Fly   248 LSIHLKRHYNQRDFPCPQPECGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHLKV 312
            |:.|...|..::.|.|  .||||.|..:|.|..|:|.||:::|:.|..|...|.|.|:..:|.::
Human   331 LTRHKMIHTGEKPFQC--EECGKAFNRSSHLTQHKIIHTKEKPYKCEECGKAFNRSSHLTKHKRI 393

  Fly   313 HER 315
            |.|
Human   394 HTR 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	7/19 (37%)
		zf-H2C2_2	113..138	CDD:290200	16/24 (67%)
		C2H2 Zn finger	129..149	CDD:275368	9/19 (47%)
		zf-H2C2_2	142..166	CDD:290200	13/23 (57%)
		COG5048	151..>264	CDD:227381	30/119 (25%)
		C2H2 Zn finger	157..177	CDD:275368	8/19 (42%)
		C2H2 Zn finger	185..206	CDD:275368	7/27 (26%)
		C2H2 Zn finger	235..255	CDD:275368	4/19 (21%)
		C2H2 Zn finger	263..285	CDD:275368	10/21 (48%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
ZNF257	NP_258429.2	KRAB	4..64	CDD:214630
		KRAB	4..43	CDD:279668
		COG5048	<157..474	CDD:227381	83/263 (32%)
		C2H2 Zn finger	175..195	CDD:275368	3/19 (16%)
		C2H2 Zn finger	203..223	CDD:275368	7/19 (37%)
		zf-H2C2_2	215..240	CDD:290200	16/24 (67%)
		C2H2 Zn finger	231..251	CDD:275368	9/19 (47%)
		zf-H2C2_2	243..268	CDD:290200	13/24 (54%)
		C2H2 Zn finger	259..279	CDD:275368	8/19 (42%)
		C2H2 Zn finger	288..310	CDD:275368	4/21 (19%)
		zf-H2C2_2	303..327	CDD:290200	8/47 (17%)
		C2H2 Zn finger	318..338	CDD:275368	4/19 (21%)
		zf-H2C2_2	330..355	CDD:290200	10/26 (38%)
		C2H2 Zn finger	346..366	CDD:275368	10/21 (48%)
		zf-H2C2_2	358..383	CDD:290200	9/24 (38%)
		C2H2 Zn finger	374..394	CDD:275368	6/19 (32%)
		zf-H2C2_2	418..442	CDD:290200
		C2H2 Zn finger	433..453	CDD:275368
		zf-H2C2_2	445..470	CDD:290200
		C2H2 Zn finger	461..481	CDD:275368
		zf-H2C2_2	473..498	CDD:290200
		C2H2 Zn finger	489..509	CDD:275368
		zf-H2C2_2	501..526	CDD:290200
		C2H2 Zn finger	517..537	CDD:275368
		C2H2 Zn finger	545..561	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.000