Protein Alignment CG10958 and drc1

DIOPT Version :10

• Sequence 1: NP_572445.1
• Gene: CG10958 / 31736
• FlyBaseID: FBgn0030004
• Length: 743
• Species: Drosophila melanogaster
• Sequence 2: NP_001120940.1
• Gene: drc1 / 100034551
• ZFINID: ZDB-GENE-041001-218
• Length: 670
• Species: Danio rerio
• Alignment Length: 753
• Identity: 210/753 - (27%)
• Similarity: 349/753 - (46%)
• Gaps: 110/753 - (14%)

  Fly    11 HQ-ELVSDGSVEEEEEVEPDLGPVDSWESFNDRIDGLIFNERCDKSVKKLDERRLAILNRVRQQF 74
            || |..:.|  ||.||:.|      |.||              ||..:::..|||.:..|...|.
Zfish     2 HQTEAFAAG--EEAEELRP------SVES--------------DKKEERILARRLRLAARKEAQT 44

  Fly    75 RE-------APKGVAERCQAQKSPIDQRLELSSERLNELVRFGKELVTNVRVANERRELNRR--L 130
            |:       ..:.|.|..:..:..::.|    ..|:.:|...|.|||||::||.:.||.:||  |
Zfish    45 RQRLGEDDLGKEDVKEETRKSQKEVEHR----ERRMAKLKSDGLELVTNIQVAADARESDRRTEL 105

  Fly   131 FEGAQKNQMHVKLQRESVETMARFENIKARWTELEETNEPMLLWDQIEEQKKRIAEIMARKDEMI 195
            .||.:..:  .||:.|:..:..:||.|..:||:.:....|:.|.|.:..|::...:|:|.|:::|
Zfish   106 EEGHRLRR--EKLENEAKSSQEKFEEINRKWTDAKMKQTPLDLRDALSSQQQLCEQIIADKNKLI 168

  Fly   196 SACQAEVDRMNAKYEFDRERQAQDLCCLVERVDHQVETLKEAYKEHIQMLRQTIEEERQIFADNA 260
            |..|.|:...:.:|..|.:|||:|:..||||::.|:.|||::|:|.:..:..:::|||:......
Zfish   169 SELQQELKASDDRYVKDLKRQAKDIDLLVERMEEQISTLKKSYREDLHQIENSLDEERRTLLTKH 233

  Fly   261 VEKWRTFFDAMNANFDEKANLVRARE--QFYARQTQQINESQEELTKSTRIRLEKECERLELELR 323
            .:||.  .:..:.|..|..|::::..  :.||...|::.....|.....:||::.|.::|.::::
Zfish   234 KKKWE--HERKDRNEKELKNMMQSLSVMEEYADLLQKLRVQTAEEYNIDKIRMDTEVQKLRMKVQ 296

  Fly   324 RTRDNVLMNSEKLDYNYQVLQKRNEENVIINNQQKRRVARLHEAIGRTRRGLKNLYNTGKRNIAR 388
            :|:.|..||.|||||.|:||:|:.|||.||.:|.||::.|:.:.:...:..|.......|.....
Zfish   297 QTKFNCHMNEEKLDYKYEVLKKKEEENAIIKSQLKRKIIRMQDVLNNLKSKLTKQEKQSKAGNQS 361

  Fly   389 LSSDIYKLHSNINDMESKAHQARLNNREKFDRIWEINYKELNLLVDRVYHIDRIIHEQQLAMPWS 453
            ||:|..::.....|::.||......:.|:.:::|.:...|...|..|....||:||||||.:.|:
Zfish   362 LSNDYTRISQQYKDIQKKARHFAALDAERLEKLWLMCEDEAKALTHRALETDRVIHEQQLGLEWA 426

  Fly   454 SPVPPIPNINKAKKKRNNILEKFDMRIGRVPKNRVMPNSGVNCKPDIKELPPDSL-----RLMRN 513
            |  ||:|.:.::...:...............|..  |..|         |..|:.     |.:::
Zfish   427 S--PPLPFMERSGAVQQKTFRTATQAAADTLKGE--PGGG---------LDEDTAAGLNKRTVKS 478

  Fly   514 LIRKLSDRGGFLIEERLLKILEPYSEEEKCLVRIDNIFAALRIRHLRDVKELTKVFMPYTYCPNC 578
            ::..|.|..|||:|.:||.:|.|..:.|:.|:::|.||:|:.|...:||.::.:.||.|
Zfish   479 ILELLCDEMGFLVESKLLMLLSPLEKNEQSLIKLDAIFSAIGIESEKDVYKMAEFFMNY------ 537

  Fly   579 QPQGLSPRKCAEVFMKDQKPNRLQGAAGGQPDEKEHRS----TGDTFLPKSEVAAKRCHNHYLVM 639
                   |:....:.||:       .|.||.:..|..|    |.|......:..|:.|...
Zfish   538 -------RQHESKYTKDE-------TANGQGESAEELSNLIHTEDLLAALKDFTAQFCRQD---- 584

  Fly   640 EPALCLHAMNLFTSKMHKKMYEHEPGSILNAVNLIQITDAEIRNFWRQFSACFPASKCKLWKTLE 704
                        ....||       .|||   .|....|:|...:|...:...|.||.|||..|:
Zfish   585 ------------VQASHK-------SSIL---GLDMRDDSEDAVYWESIANVMPESKLKLWDALD 627

  Fly   705 HGLNHYVEVLKMRVQYDAEVVFLRRQNEELRHLLQKFT 742
            ..||.|..||..|.:...|...:::||.|||.||..:|
Zfish   628 TALNKYHAVLTERTELLMETQNIQQQNSELRQLLHLYT 665

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10958	NP_572445.1	NYD-SP28	119..220	CDD:464307	33/102 (32%)
		SMC_prok_B	<123..>424	CDD:274008	90/304 (30%)
		NYD-SP28_assoc	684..741	CDD:464309	22/56 (39%)
drc1	NP_001120940.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		14/45 (31%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	39..72		5/32 (16%)
		SMC_N	42..>390	CDD:481474	103/355 (29%)
		NYD-SP28	92..193	CDD:464307	33/102 (32%)
		NYD-SP28_assoc	607..664	CDD:464309	22/56 (39%)