Protein Alignment CG2116 and ZNF551

DIOPT Version :9

• Sequence 1: NP_572444.2
• Gene: CG2116 / 31735
• FlyBaseID: FBgn0030003
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: NP_612356.2
• Gene: ZNF551 / 90233
• HGNCID: 25108
• Length: 670
• Species: Homo sapiens
• Alignment Length: 268
• Identity: 75/268 - (27%)
• Similarity: 117/268 - (43%)
• Gaps: 44/268 - (16%)

  Fly   241 FSMISDIMDE------KLPVECGIC-PDVMHKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYL 298
            ||..|::::.      :.|.|||.| ......|.|.:|.:.|  .|...|.|..|.:::|....|
Human   344 FSYKSNLIEHQRVHTGERPYECGECGKSFRQSSSLFRHQRVH--SGERPYQCCECGKSFRQIFNL 406

  Fly   299 AGHARRHMGIRPYVCELCTLYFSTKQDLRVHNQRRHL-EKEHICEVCGKTFAQNTQLKRHREATH 362
            ..|.|.|.|..||.|..|...||.|.:| :.:||.|. |:.:.|..|||:|.|.:.|.||| :.|
Human   407 IRHRRVHTGEMPYQCSDCGKSFSCKSEL-IQHQRIHSGERPYECRECGKSFRQFSNLIRHR-SIH 469

  Fly   363 EKKRRFQCEYCQKAYYKNFSLQEHIRNVHMGKR---------------------------RMLKC 400
            ...|.::|..|:|::.:.|.|.:|.| ||.|:|                           |..:|
Human   470 TGDRPYECSECEKSFSRKFILIQHQR-VHTGERPYECSECGKSFTRKSDLIQHRRIHTGTRPYEC 533

  Fly   401 PFCGMQCRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFDAHKRSIQCRSNTRRFVNADGNR 465
            ..||...|....:.:||: :|..:..|.|..|.:.|:..:....|:|   ..:..|.:..::..:
Human   534 SECGKSFRQRSGLIQHRR-LHTGERPYECSECGKSFSQSASLIQHQR---VHTGERPYECSECGK 594

  Fly   466 EGSDSESI 473
            ..|.|.|:
Human   595 SFSQSSSL 602

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	6/19 (32%)
		C2H2 Zn finger	285..305	CDD:275368	6/19 (32%)
		PHA00733	<308..357	CDD:177301	19/49 (39%)
		C2H2 Zn finger	313..334	CDD:275368	8/20 (40%)
		C2H2 Zn finger	341..362	CDD:275368	10/20 (50%)
		C2H2 Zn finger	370..388	CDD:275368	6/17 (35%)
		C2H2 Zn finger	400..418	CDD:275370	5/17 (29%)
		C2H2 Zn finger	429..447	CDD:275368	4/17 (24%)
ZNF551	NP_612356.2	KRAB	29..>71	CDD:214630
		KRAB	29..68	CDD:279668
		C2H2 Zn finger	253..273	CDD:275368
		COG5048	279..624	CDD:227381	75/268 (28%)
		C2H2 Zn finger	281..301	CDD:275368
		C2H2 Zn finger	311..329	CDD:275368
		C2H2 Zn finger	337..357	CDD:275368	3/12 (25%)
		zf-H2C2_2	349..374	CDD:290200	5/24 (21%)
		C2H2 Zn finger	365..385	CDD:275368	6/19 (32%)
		zf-H2C2_2	377..402	CDD:290200	7/26 (27%)
		C2H2 Zn finger	393..413	CDD:275368	6/19 (32%)
		zf-H2C2_2	405..430	CDD:290200	10/24 (42%)
		C2H2 Zn finger	421..441	CDD:275368	8/20 (40%)
		zf-H2C2_2	433..458	CDD:290200	10/25 (40%)
		C2H2 Zn finger	449..469	CDD:275368	10/20 (50%)
		zf-H2C2_2	461..486	CDD:290200	9/25 (36%)
		C2H2 Zn finger	477..497	CDD:275368	7/20 (35%)
		zf-H2C2_2	490..514	CDD:290200	7/24 (29%)
		C2H2 Zn finger	505..525	CDD:275368	0/19 (0%)
		zf-H2C2_2	517..542	CDD:290200	4/24 (17%)
		C2H2 Zn finger	533..553	CDD:275368	6/20 (30%)
		zf-H2C2_2	546..570	CDD:290200	7/24 (29%)
		C2H2 Zn finger	561..581	CDD:275368	5/22 (23%)
		zf-H2C2_2	573..598	CDD:290200	3/27 (11%)
		C2H2 Zn finger	589..609	CDD:275368	3/14 (21%)
		C2H2 Zn finger	617..637	CDD:275368
		zf-H2C2_2	629..654	CDD:290200
		C2H2 Zn finger	645..665	CDD:275368

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910