DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2116 and ZNF732

DIOPT Version :9

Sequence 1:NP_572444.2 Gene:CG2116 / 31735 FlyBaseID:FBgn0030003 Length:598 Species:Drosophila melanogaster
Sequence 2:NP_001131080.1 Gene:ZNF732 / 654254 HGNCID:37138 Length:585 Species:Homo sapiens


Alignment Length:199 Identity:64/199 - (32%)
Similarity:95/199 - (47%) Gaps:7/199 - (3%)


- Green bases have known domain annotations that are detailed below.


  Fly   250 EKLPVECGICPDVM-HKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVC 313
            |:.|..|..|..:: ..|.::||.|.|  .|...|.|..|.:.:.....|..|.|.|.|.:||.|
Human   274 EEKPFTCEECGKIITSSSNVAKHKKIH--TGEKLYKCQECGKVFNRSTTLTKHNRIHTGEKPYTC 336

  Fly   314 ELCTLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYY 378
            |.|...||....|..|.:....||.:.||.|||.|.|:..|.:|: :.|..::.:.||.|.||:.
Human   337 EECGKAFSRSSVLNEHKRIHTGEKPYKCEQCGKAFRQSATLNKHK-SIHTGEKPYTCEECGKAFS 400

  Fly   379 KNFSLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFD 443
            :..:|.|| :.:|.|:|.. ||..||.....:..:.:| |.:|..:..|.|..|.:.|...:|..
Human   401 RFTTLNEH-KRIHTGERPH-KCEECGKAFGWSTDLNKH-KIIHTGEKPYKCEECGKAFGWSAYLS 462

  Fly   444 AHKR 447
            .||:
Human   463 KHKK 466

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2116NP_572444.2 C2H2 Zn finger 256..275 CDD:275368 6/19 (32%)
C2H2 Zn finger 285..305 CDD:275368 5/19 (26%)
PHA00733 <308..357 CDD:177301 19/48 (40%)
C2H2 Zn finger 313..334 CDD:275368 7/20 (35%)
C2H2 Zn finger 341..362 CDD:275368 9/20 (45%)
C2H2 Zn finger 370..388 CDD:275368 8/17 (47%)
C2H2 Zn finger 400..418 CDD:275370 4/17 (24%)
C2H2 Zn finger 429..447 CDD:275368 5/17 (29%)
ZNF732NP_001131080.1 KRAB 4..62 CDD:214630
KRAB 4..43 CDD:279668
COG5048 130..542 CDD:227381 64/199 (32%)
C2H2 Zn finger 143..163 CDD:275368
C2H2 Zn finger 170..189 CDD:275368
C2H2 Zn finger 225..244 CDD:275368
C2H2 Zn finger 253..272 CDD:275368
C2H2 Zn finger 280..300 CDD:275368 6/19 (32%)
zf-H2C2_2 292..317 CDD:290200 8/26 (31%)
C2H2 Zn finger 308..328 CDD:275368 5/19 (26%)
zf-H2C2_2 321..345 CDD:290200 11/23 (48%)
C2H2 Zn finger 336..356 CDD:275368 7/19 (37%)
zf-H2C2_2 349..373 CDD:290200 10/23 (43%)
C2H2 Zn finger 364..384 CDD:275368 9/20 (45%)
zf-H2C2_2 377..401 CDD:290200 8/24 (33%)
C2H2 Zn finger 392..412 CDD:275368 8/20 (40%)
zf-H2C2_2 405..427 CDD:290200 10/23 (43%)
C2H2 Zn finger 420..440 CDD:275368 5/20 (25%)
zf-H2C2_2 432..455 CDD:290200 6/23 (26%)
C2H2 Zn finger 448..468 CDD:275368 6/19 (32%)
zf-H2C2_2 460..483 CDD:290200 3/7 (43%)
C2H2 Zn finger 476..496 CDD:275368
zf-H2C2_2 488..511 CDD:290200
C2H2 Zn finger 504..524 CDD:275368
zf-H2C2_2 516..541 CDD:290200
C2H2 Zn finger 532..552 CDD:275368
C2H2 Zn finger 560..579 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.910

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