DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and Zfp112

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	XP_036009176.1	Gene:	Zfp112 / 57745	MGIID:	1929115	Length:	883	Species:	Mus musculus

Alignment Length:	196	Identity:	64/196 - (32%)
Similarity:	96/196 - (48%)	Gaps:	7/196 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 PVECGICPDVMHK-SKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCELC 316
            |.:||.|.....| |.|..|.:.|  .|...|.|..|.:.:....||..|...|.|.||::||:|
Mouse   638 PYKCGECGKGFSKASTLLAHERVH--TGEKPYQCHECGKNFSQKSYLQSHQSVHSGERPHICEVC 700

  Fly   317 TLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYYKNF 381
            ...||.:..|:.|.:.....|.:.||||||.|:|.::|:.| :..|..::.|:||.|.|.:.::.
Mouse   701 GKGFSQRAYLQGHLRVHTRVKPYKCEVCGKGFSQGSRLEAH-QRVHTGRKPFKCETCTKGFSESS 764

  Fly   382 SLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFDAHK 446
            .||.|.| :| .:.|..||..||........:..|.: :|..:..|.|.:|.:.|:..|...||:
Mouse   765 RLQAHQR-IH-EEGRPYKCDQCGKGFSGYSSLQAHHR-VHTGEKPYKCEVCGKGFSQRSNLQAHQ 826

  Fly   447 R 447
            |
Mouse   827 R 827

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	7/19 (37%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		PHA00733	<308..357	CDD:177301	19/48 (40%)
		C2H2 Zn finger	313..334	CDD:275368	7/20 (35%)
		C2H2 Zn finger	341..362	CDD:275368	10/20 (50%)
		C2H2 Zn finger	370..388	CDD:275368	7/17 (41%)
		C2H2 Zn finger	400..418	CDD:275370	4/17 (24%)
		C2H2 Zn finger	429..447	CDD:275368	6/17 (35%)
Zfp112	XP_036009176.1	KRAB	12..72	CDD:214630
		COG5048	251..716	CDD:227381	27/79 (34%)
		C2H2 Zn finger	481..498	CDD:275368
		C2H2 Zn finger	529..549	CDD:275368
		C2H2 Zn finger	557..577	CDD:275368
		C2H2 Zn finger	585..605	CDD:275368
		C2H2 Zn finger	613..633	CDD:275368
		C2H2 Zn finger	641..661	CDD:275368	7/19 (37%)
		C2H2 Zn finger	669..689	CDD:275368	5/19 (26%)
		COG5048	<674..842	CDD:227381	51/158 (32%)
		C2H2 Zn finger	697..717	CDD:275368	7/19 (37%)
		C2H2 Zn finger	725..745	CDD:275368	10/20 (50%)
		C2H2 Zn finger	753..773	CDD:275368	8/20 (40%)
		C2H2 Zn finger	781..801	CDD:275368	4/20 (20%)
		C2H2 Zn finger	809..829	CDD:275368	7/19 (37%)
		C2H2 Zn finger	837..857	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910