DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and prdm1

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	XP_002937203.1	Gene:	prdm1 / 493207	XenbaseID:	XB-GENE-853254	Length:	784	Species:	Xenopus tropicalis

Alignment Length:	307	Identity:	71/307 - (23%)
Similarity:	115/307 - (37%)	Gaps:	71/307 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   150 PPSSPS------LPPSPPRP---PSPVVQPASKARNSARQI-ALRSFVSQKNNDDDDGS------ 198
            |.|.|.      |.|..||.   |:|         |||..| ...:.:..|.:....||
Frog   427 PGSLPHEGGRRLLQPELPRDFLIPAP---------NSAFSITGAAASMKDKQSSPTSGSPTAGTA 482

  Fly   199 -----VKEVKP--------SEKMLEEFKGPRRYMLFDDLIATIVDFDEDSTPLVEFSMISDIMDE 250
                 :.:.||        ||:.:...|..|....:..|          ..||.:       .:.
Frog   483 ASLEHIMQPKPTSAVMSTSSEEAINLIKSKRNMTGYKTL----------PYPLKK-------QNG 530

  Fly   251 KLPVECGICPDVMHK-SKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCE 314
            |:..||.:|.....: |.|..|.:.|  .|...:.|..|.:.:....:|..|...|.|.:|:.|:
Frog   531 KIKYECNVCSKTFGQLSNLKVHLRVH--SGERPFKCQTCNKGFTQLAHLQKHFLVHTGEKPHECQ 593

  Fly   315 LCTLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYYK 379
            :|...||:..:|:.|.:....||.:.|::|...|.|...||.|:. .|.::|..:|.:|.|:|..
Frog   594 VCHKRFSSTSNLKTHLRLHSGEKPYQCKLCPAKFTQFVHLKLHKR-LHTRERPHKCIHCHKSYIH 657

  Fly   380 NFSLQEHIRNVHMGKRRMLKCPF---CGMQCRDAHKMARHRKEMHLS 423
            ..||..|::.         .||.   .|:...|.::|....::..:|
Frog   658 LCSLNFHMKG---------NCPVSPRLGVSREDLNRMNEEIEKFDIS 695

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	5/19 (26%)
		C2H2 Zn finger	285..305	CDD:275368	4/19 (21%)
		PHA00733	<308..357	CDD:177301	15/48 (31%)
		C2H2 Zn finger	313..334	CDD:275368	6/20 (30%)
		C2H2 Zn finger	341..362	CDD:275368	7/20 (35%)
		C2H2 Zn finger	370..388	CDD:275368	7/17 (41%)
		C2H2 Zn finger	400..418	CDD:275370	5/20 (25%)
		C2H2 Zn finger	429..447	CDD:275368
prdm1	XP_002937203.1	PR-SET_PRDM1	45..172	CDD:380964
		COG5048	<446..647	CDD:227381	51/229 (22%)
		C2H2 Zn finger	536..556	CDD:275368	5/19 (26%)
		C2H2 Zn finger	564..584	CDD:275368	4/19 (21%)
		zf-H2C2_2	576..601	CDD:372612	8/24 (33%)
		C2H2 Zn finger	592..612	CDD:275368	6/19 (32%)
		C2H2 Zn finger	620..640	CDD:275368	7/20 (35%)
		C2H2 Zn finger	648..666	CDD:275368	7/17 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910