DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and AgaP_AGAP008232

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	XP_317239.4	Gene:	AgaP_AGAP008232 / 4578130	VectorBaseID:	AGAP008232	Length:	966	Species:	Anopheles gambiae

Alignment Length:	177	Identity:	52/177 - (29%)
Similarity:	83/177 - (46%)	Gaps:	9/177 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly   248 MDEK--LPVECGICPDVMHK-SKLSKHHK-THLVPGTNRYACIYCTETYRDCKYLAGH-ARRHMG 307
            :|::  :...|.:|....|. .:|..|.. :|..| .:.|.|..|...|.....|..| |..|..
Mosquito   205 LDDEHGIDARCVVCDRQCHDIDQLDDHLVISHHYP-KDAYRCELCPRAYSYRPSLLRHRAIVHGE 268

  Fly   308 IRPYVCELCTLYFSTKQDLRVHNQRRHL-EKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCE 371
            :|.:.||.|...|:...:|:.|.:..|: .:.|.|..||||||.::.||:|.. .|...:.||||
Mosquito   269 LRRFPCENCPKVFTDPSNLQRHIRTHHVGARSHACPECGKTFATSSGLKQHTH-IHSSVKPFQCE 332

  Fly   372 YCQKAYYKNFSLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRK 418
            .|.|:|.:..:|..| |.:|...:..:||..||........:::|::
Mosquito   333 VCFKSYTQFSNLCRH-RRMHADCQVQIKCNKCGDSFSTTTSLSKHKR 378

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	5/20 (25%)
		C2H2 Zn finger	285..305	CDD:275368	6/20 (30%)
		PHA00733	<308..357	CDD:177301	18/49 (37%)
		C2H2 Zn finger	313..334	CDD:275368	6/20 (30%)
		C2H2 Zn finger	341..362	CDD:275368	10/20 (50%)
		C2H2 Zn finger	370..388	CDD:275368	7/17 (41%)
		C2H2 Zn finger	400..418	CDD:275370	4/17 (24%)
		C2H2 Zn finger	429..447	CDD:275368
AgaP_AGAP008232	XP_317239.4	C2H2 Zn finger	215..237	CDD:275368	5/21 (24%)
		C2H2 Zn finger	245..266	CDD:275368	6/20 (30%)
		zf-C2H2	272..294	CDD:278523	6/21 (29%)
		C2H2 Zn finger	274..294	CDD:275368	6/19 (32%)
		zf-H2C2_2	286..312	CDD:290200	10/25 (40%)
		C2H2 Zn finger	303..323	CDD:275368	10/20 (50%)
		zf-C2H2_8	304..384	CDD:292531	26/77 (34%)
		zf-C2H2	329..351	CDD:278523	10/22 (45%)
		C2H2 Zn finger	331..351	CDD:275368	8/20 (40%)
		C2H2 Zn finger	360..378	CDD:275368	4/17 (24%)
		COG5048	820..>872	CDD:227381
		zf-C2H2	820..842	CDD:278523
		C2H2 Zn finger	822..842	CDD:275368
		zf-H2C2_2	834..858	CDD:290200
		C2H2 Zn finger	850..871	CDD:275368
		zf-C2H2	877..899	CDD:278523
		C2H2 Zn finger	879..899	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910