DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and zgc:101130

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_001037792.1	Gene:	zgc:101130 / 445160	ZFINID:	ZDB-GENE-040801-72	Length:	372	Species:	Danio rerio

Alignment Length:	313	Identity:	82/313 - (26%)
Similarity:	129/313 - (41%)	Gaps:	61/313 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   186 FVSQKNNDDDDGSVKE--VKPSEKMLEEFKGPRRYMLFDDLIATIVDFDEDSTPLVEFSMISDIM 248
            |..|:    |...|||  .|.:|:..||.:.|..|.:.::..:|:   ...:|.|..:
Zfish     7 FAEQR----DLMEVKEEPTKLNEEEEEEEEPPSIYYITEENPSTL---SPTATKLKNY------- 57

  Fly   249 DEKLPVECGIC-PDVMHKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYV 312
                  .|.|| .....|.:|.:|.:||  .|...:||:.|.:::...:.||.||:.|.|.:||.
Zfish    58 ------VCSICEKSFARKYRLDRHVRTH--TGEKPFACVECAKSFACKEKLARHAKIHTGEKPYT 114

  Fly   313 CELCTLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAY 377
            |.||....:.|..|:.|......||.|:|..|||.|..|..|:||.: .|..:|...|..|.|.:
Zfish   115 CSLCGKSLACKTRLKRHMNTHTGEKPHVCLQCGKCFTCNASLQRHVK-LHTGERPHICRECGKGF 178

  Fly   378 YKNFSLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHR---------------KE-------- 419
            .:|..|..|: .:|.|:|..: |..||...|..:.:..|:               ||
Zfish   179 IRNEKLISHM-TIHTGERPFI-CDECGKSFRHVNGLRDHQLSHSAVKSFPCDQCNKEFITPSALK 241

  Fly   420 ----MHLSQGTYVCHLCQEEFTDISYFDAHK------RSIQCRSNTRRFVNAD 462
                :|..:..|:|.||...|:.:..|..|:      :...|....:.|:.:|
Zfish   242 RHLRVHSGEKPYLCTLCGRSFSRVDIFKRHQEVHIGVKDHVCFECGKAFITSD 294

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	6/19 (32%)
		C2H2 Zn finger	285..305	CDD:275368	6/19 (32%)
		PHA00733	<308..357	CDD:177301	18/48 (38%)
		C2H2 Zn finger	313..334	CDD:275368	6/20 (30%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		C2H2 Zn finger	370..388	CDD:275368	6/17 (35%)
		C2H2 Zn finger	400..418	CDD:275370	5/32 (16%)
		C2H2 Zn finger	429..447	CDD:275368	6/23 (26%)
zgc:101130	NP_001037792.1	COG5048	43..>334	CDD:227381	70/273 (26%)
		C2H2 Zn finger	59..79	CDD:275368	6/19 (32%)
		zf-H2C2_2	72..96	CDD:290200	8/25 (32%)
		C2H2 Zn finger	87..107	CDD:275368	6/19 (32%)
		C2H2 Zn finger	115..135	CDD:275368	6/19 (32%)
		zf-H2C2_2	128..152	CDD:290200	10/23 (43%)
		C2H2 Zn finger	143..163	CDD:275368	9/20 (45%)
		C2H2 Zn finger	171..191	CDD:275368	6/20 (30%)
		C2H2 Zn finger	199..219	CDD:275368	5/19 (26%)
		C2H2 Zn finger	227..247	CDD:275368	2/19 (11%)
		zf-H2C2_2	239..264	CDD:290200	6/24 (25%)
		C2H2 Zn finger	255..275	CDD:275368	6/19 (32%)
		C2H2 Zn finger	283..303	CDD:275368	3/12 (25%)
		zf-H2C2_2	296..320	CDD:290200
		C2H2 Zn finger	311..331	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910