DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2116 and CG14710

DIOPT Version :9

Sequence 1:NP_572444.2 Gene:CG2116 / 31735 FlyBaseID:FBgn0030003 Length:598 Species:Drosophila melanogaster
Sequence 2:NP_650092.4 Gene:CG14710 / 41393 FlyBaseID:FBgn0037920 Length:415 Species:Drosophila melanogaster


Alignment Length:451 Identity:103/451 - (22%)
Similarity:163/451 - (36%) Gaps:158/451 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MSHKRCLANEVIEFV--------LPANSD-YSDEDNRGNVRVINTSDDATYV--LLDNL------ 48
            :..|.|  |...|||        :..||. |.:..:......:..:.||.|:  |.:||      
  Fly    52 LPEKAC--NSCCEFVQMWFNFRQMCLNSQVYWETSSSERPEALAQASDAEYMLYLYENLHLKLGT 114

  Fly    49 GNEFEEDIIIVNENGVEKEMLMSKELRDF----------------------IVGSRVKDLTDDEQ 91
            .|:.:|:|..: |.|.|::...|:|:.||                      |:.|.:....||:|
  Fly   115 ENQEKEEITAI-EEGDEQQEDQSQEVLDFNGFIINESIEEDEEPNTESPEQILISHMDSYVDDQQ 178

  Fly    92 MPQFVVRELDMSEVGDLVEVEPEMEQ-----EADYGDYGDYEHEPSYGHPRDNERVEEDLDMYPP 151
            |.:.:      .:.|:|||   |:..     |.:|||                    |:|.|  .
  Fly   179 MEELI------DDKGELVE---ELSNANTFYEVEYGD--------------------EELLM--S 212

  Fly   152 SSPSLPPS-------PPRPPSPVVQPASKARNSARQIALRSFVSQKNNDDDDGSVKEVKPSEKML 209
            |:||..||       |.||..|..:...|.::.              |..:.|:..:.|..||.:
  Fly   213 SAPSPHPSFKMDKQKPGRPRKPDAELKFKRKDI--------------NAKERGNQPKCKEEEKFM 263

  Fly   210 EEFKGPRRYMLFDDLIATIVDFDEDSTPLVEFSMISDIMDEKLPVECGICPDVMH-KSKLSKHHK 273
                                                          |.:|.:|.: ||..:.|..
  Fly   264 ----------------------------------------------CILCGNVFYKKSVFTAHMM 282

  Fly   274 THLVPGTNRY---ACIYCTETYRDCKYLAGHARRHMGIRPYVCELCTLYFSTKQDLRVHNQRRHL 335
            ||     :.|   .|..|.:::|....|..|.|||.|.|||.|..|..:|..:.: ||.::|.|.
  Fly   283 TH-----SEYKPHQCEICNKSFRQMGELRAHIRRHTGDRPYKCMYCDRHFYDRSE-RVRHERVHT 341

  Fly   336 E-KEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYYKNFSLQEHIRNV-HMGK 394
            . :.:.|:.|||||.....||.| ..:|..::.:.|..|.|::.....|:.|::.: |..|
  Fly   342 NTRPYACQECGKTFTHTAILKNH-ILSHSAQKNYNCGICCKSFTLLHQLKAHLQTLTHRNK 401

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2116NP_572444.2 C2H2 Zn finger 256..275 CDD:275368 6/19 (32%)
C2H2 Zn finger 285..305 CDD:275368 6/19 (32%)
PHA00733 <308..357 CDD:177301 18/49 (37%)
C2H2 Zn finger 313..334 CDD:275368 6/20 (30%)
C2H2 Zn finger 341..362 CDD:275368 9/20 (45%)
C2H2 Zn finger 370..388 CDD:275368 5/17 (29%)
C2H2 Zn finger 400..418 CDD:275370
C2H2 Zn finger 429..447 CDD:275368
CG14710NP_650092.4 zf-AD 9..83 CDD:285071 9/32 (28%)
COG5048 <261..395 CDD:227381 44/186 (24%)
C2H2 Zn finger 264..284 CDD:275368 6/19 (32%)
zf-C2H2 290..312 CDD:278523 6/21 (29%)
C2H2 Zn finger 292..312 CDD:275368 6/19 (32%)
zf-H2C2_2 304..327 CDD:290200 11/22 (50%)
C2H2 Zn finger 320..340 CDD:275368 6/20 (30%)
zf-H2C2_2 335..357 CDD:290200 8/21 (38%)
C2H2 Zn finger 348..368 CDD:275368 9/20 (45%)
C2H2 Zn finger 376..395 CDD:275368 5/18 (28%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45446682
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
10.930

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