DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and ZNF793

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_001013681.2	Gene:	ZNF793 / 390927	HGNCID:	33115	Length:	406	Species:	Homo sapiens

Alignment Length:	176	Identity:	54/176 - (30%)
Similarity:	86/176 - (48%)	Gaps:	14/176 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly   255 ECG--ICPDVMHKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCELCT 317
            |||  .|    :||:..:|.::|  .|...|.|..|.:.:.....|..|.|.|.|:||:.|..|.
Human   231 ECGKAFC----YKSEFIRHQRSH--TGEKPYGCTDCGKAFSHKSTLIKHQRIHTGVRPFECFFCG 289

  Fly   318 LYFSTKQDLRVHNQRRHL-EKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYYKNF 381
            ..| |::..|..:||.|. |:..:|..|||:|.:.:.|..||: .|..:|.::|..|.|::.:..
Human   290 KAF-TQKSHRTEHQRTHTGERPFVCSECGKSFGEKSYLNVHRK-MHTGERPYRCRECGKSFSQKS 352

  Fly   382 SLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTY 427
            .|.:|.| .|.|: :...|..||........::||:| :|..:..|
Human   353 CLNKHWR-THTGE-KPYGCNECGKAFYQKPNLSRHQK-IHARKNAY 395

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	6/20 (30%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		PHA00733	<308..357	CDD:177301	17/49 (35%)
		C2H2 Zn finger	313..334	CDD:275368	7/20 (35%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		C2H2 Zn finger	370..388	CDD:275368	5/17 (29%)
		C2H2 Zn finger	400..418	CDD:275370	5/17 (29%)
		C2H2 Zn finger	429..447	CDD:275368
ZNF793	NP_001013681.2	KRAB	8..68	CDD:214630
		C2H2 Zn finger	190..221	CDD:275368
		COG5048	<225..385	CDD:227381	49/163 (30%)
		C2H2 Zn finger	229..249	CDD:275368	7/21 (33%)
		C2H2 Zn finger	257..277	CDD:275368	5/19 (26%)
		C2H2 Zn finger	285..305	CDD:275368	7/20 (35%)
		C2H2 Zn finger	313..333	CDD:275368	8/20 (40%)
		C2H2 Zn finger	341..361	CDD:275368	6/20 (30%)
		C2H2 Zn finger	369..389	CDD:275368	6/20 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4954
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050