DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and CG30431

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster

Alignment Length:	339	Identity:	87/339 - (25%)
Similarity:	122/339 - (35%)	Gaps:	96/339 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly   104 EVGDL--------------VEVEPEME----QEADYGDYGDYEHE-PSYGHPRDNERVEEDLDMY 149
            |||.|              ..|.|.||    :..|:.|....||: |||.        |..:|..
  Fly   110 EVGSLEGPMSVPLQASKPVAHVAPLMETVDFESLDFQDSSHSEHDIPSYW--------ESSVDSG 166

  Fly   150 PPSSPSLPP--------SPPRPPSPVVQPASKARNSARQIALRSFVSQKNNDDDDGSVKEVKPSE 206
            ..::|...|        .||.||....:||..|   |.:..:|....:::|         |||.|
  Fly   167 SLNTPHHQPETAELFAVEPPTPPESSEEPAPDA---AEKPKMRRARPRQDN---------VKPKE 219

  Fly   207 KMLE--------------EFKGPRRYMLFDDLIATIVDFDEDSTPLVEFSMISDIMDEKLPVECG 257
            :...              |.|..|.:.|  .|..|.|..                |.| :..:|.
  Fly   220 RKASGAVHPRSLHPCPECEKKFTRNFQL--KLHMTAVHG----------------MGE-MRYQCE 265

  Fly   258 ICPDVMHKSKLSKHH-KTHL--VPGTNR-YACIYCTETYRDCKYLAGHARRHMG---IRPYVCEL 315
            .|    .|:..|:|. :.|:  |..|.| :.|.:|...:.....|..|.|.|.|   .|.:.|:.
  Fly   266 EC----RKNFASRHSLRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEAKPRIFECQR 326

  Fly   316 CTLYFSTKQDLRVHNQRRH---LEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAY 377
            |:..:.||.|||.| .|.|   :|:...|:.|.|.|.....|..|. ..|..::.|.||||.|.|
  Fly   327 CSKSWPTKSDLRTH-MRSHNPNMERPFKCDRCSKAFFTRGHLNSHL-LVHTGEKPFACEYCDKCY 389

  Fly   378 YKNFSLQEHIRNVH 391
            ....:|..|:..:|
  Fly   390 QSVGNLNNHMVRLH 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	5/19 (26%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		PHA00733	<308..357	CDD:177301	17/51 (33%)
		C2H2 Zn finger	313..334	CDD:275368	9/20 (45%)
		C2H2 Zn finger	341..362	CDD:275368	6/20 (30%)
		C2H2 Zn finger	370..388	CDD:275368	8/17 (47%)
		C2H2 Zn finger	400..418	CDD:275370
		C2H2 Zn finger	429..447	CDD:275368
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	6/22 (27%)
		C2H2 Zn finger	264..285	CDD:275368	6/24 (25%)
		C2H2 Zn finger	293..313	CDD:275368	5/19 (26%)
		zf-C2H2_8	305..373	CDD:292531	23/69 (33%)
		C2H2 Zn finger	324..344	CDD:275368	9/20 (45%)
		C2H2 Zn finger	354..374	CDD:275368	6/20 (30%)
		zf-H2C2_2	366..389	CDD:290200	9/23 (39%)
		C2H2 Zn finger	382..403	CDD:275368	8/20 (40%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446679
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930