DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and CG17328

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_609786.2	Gene:	CG17328 / 34962	FlyBaseID:	FBgn0028895	Length:	413	Species:	Drosophila melanogaster

Alignment Length:	298	Identity:	70/298 - (23%)
Similarity:	106/298 - (35%)	Gaps:	66/298 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 KEVKPSEKMLEEFKGPRRYMLFDDLIATIVDFDEDSTPLVEFSMISDIMDEKLPVECGIC----- 259
            :|.:.|:..|.::.|.......|  .||..||.|  .||:.    ....||:.||:..:.
  Fly    69 QECENSDLRLRQYLGILESWRQD--AATNTDFVE--KPLLP----QRDSDEEEPVDAKVSKRRSR 125

  Fly   260 ----PDVMHKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCELCTLYF 320
                |...||.:..|.     || ...:.|..|.::::....|..|.|.|.|.:||.|..|...|
  Fly   126 YQRKPPEEHKKRGPKP-----VP-KMPHTCYECHKSFKCIAQLTQHIRTHTGEKPYQCSFCIQRF 184

  Fly   321 STKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYYKNFSLQE 385
            :.|.:|:||.:....:|...||:|.|.|:.....:.|:: .|...|...|..|||.:|....|.:
  Fly   185 AQKYNLKVHERTHTGDKPFQCEICSKQFSALGNFQAHQK-IHLGVRDQVCSLCQKGFYTAGDLSK 248

  Fly   386 H------IRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMH----------------------- 421
            |      |:|.|        |..||........|..|:.::|
  Fly   249 HMITHTGIKNHH--------CDVCGKAFSRRRDMRTHKLKLHPLESSTNHDIVDDDDDEAIDTDP 305

  Fly   422 -----LSQGTYVCHLCQEEFTDISYFDAHKRSIQCRSN 454
                 |....:.|..|.:.|........|.|:....:|
  Fly   306 VGLDTLDHAHFKCPDCDKAFDTADSLSLHFRTHAANNN 343

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	4/27 (15%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		PHA00733	<308..357	CDD:177301	15/48 (31%)
		C2H2 Zn finger	313..334	CDD:275368	7/20 (35%)
		C2H2 Zn finger	341..362	CDD:275368	6/20 (30%)
		C2H2 Zn finger	370..388	CDD:275368	7/23 (30%)
		C2H2 Zn finger	400..418	CDD:275370	5/17 (29%)
		C2H2 Zn finger	429..447	CDD:275368	4/17 (24%)
CG17328	NP_609786.2	zf-AD	8..80	CDD:214871	3/10 (30%)
		COG5048	146..>211	CDD:227381	20/64 (31%)
		C2H2 Zn finger	149..169	CDD:275368	5/19 (26%)
		C2H2 Zn finger	177..197	CDD:275368	7/19 (37%)
		zf-H2C2_2	189..213	CDD:404364	8/23 (35%)
		C2H2 Zn finger	205..225	CDD:275368	6/20 (30%)
		C2H2 Zn finger	233..253	CDD:275368	7/19 (37%)
		zf-H2C2_2	245..270	CDD:404364	8/32 (25%)
		C2H2 Zn finger	261..282	CDD:275368	5/20 (25%)
		C2H2 Zn finger	318..338	CDD:275368	5/19 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45449805
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930