DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and crol

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_001245993.1	Gene:	crol / 34592	FlyBaseID:	FBgn0020309	Length:	962	Species:	Drosophila melanogaster

Alignment Length:	209	Identity:	62/209 - (29%)
Similarity:	95/209 - (45%)	Gaps:	13/209 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 PVECGICPDVM-HKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCELC 316
            |..|..|.... .|..|..|.:.|  .|.:.:.|.||.:|:...::|..|.|:|.|..|:.|..|
  Fly   444 PHRCDFCSKTFTRKEHLLNHVRQH--TGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYC 506

  Fly   317 TLYFSTKQDLRVHNQRRHL-EKEHICEVCGKTFAQNTQLKRH-REATHEKKRRFQCEYCQKAYYK 379
            |..| |::|..|::.|:|. |..|.|..|.|||.:...|..| |:.|.:...|  |.||:|.:.:
  Fly   507 TKAF-TRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHR--CSYCKKTFTR 568

  Fly   380 NFSLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFDA 444
            ...|..|:| :|.|.... ||.:|.........:..|.:: |.|...:.|::|.:.||...:...
  Fly   569 KEHLTNHVR-LHTGDSPH-KCEYCQKTFTRKEHLNNHMRQ-HSSDNPHCCNVCNKPFTRKEHLIN 630

  Fly   445 HKRSIQCRSNTRRF 458
            |..  :|.:..|.|
  Fly   631 HMS--RCHTGDRPF 642

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	5/19 (26%)
		C2H2 Zn finger	285..305	CDD:275368	7/19 (37%)
		PHA00733	<308..357	CDD:177301	18/49 (37%)
		C2H2 Zn finger	313..334	CDD:275368	8/20 (40%)
		C2H2 Zn finger	341..362	CDD:275368	8/21 (38%)
		C2H2 Zn finger	370..388	CDD:275368	6/17 (35%)
		C2H2 Zn finger	400..418	CDD:275370	3/17 (18%)
		C2H2 Zn finger	429..447	CDD:275368	5/17 (29%)
crol	NP_001245993.1	C2H2 Zn finger	223..243	CDD:275368
		C2H2 Zn finger	251..271	CDD:275368
		C2H2 Zn finger	279..299	CDD:275368
		COG5048	300..723	CDD:227381	62/209 (30%)
		C2H2 Zn finger	307..327	CDD:275368
		C2H2 Zn finger	335..355	CDD:275368
		C2H2 Zn finger	363..383	CDD:275368
		C2H2 Zn finger	391..411	CDD:275368
		C2H2 Zn finger	419..439	CDD:275368
		C2H2 Zn finger	447..467	CDD:275368	5/19 (26%)
		C2H2 Zn finger	475..495	CDD:275368	7/19 (37%)
		C2H2 Zn finger	503..523	CDD:275368	8/20 (40%)
		C2H2 Zn finger	531..551	CDD:275368	8/19 (42%)
		C2H2 Zn finger	559..579	CDD:275368	7/20 (35%)
		C2H2 Zn finger	587..607	CDD:275368	3/20 (15%)
		C2H2 Zn finger	615..636	CDD:275368	5/22 (23%)
		C2H2 Zn finger	644..664	CDD:275368
		C2H2 Zn finger	676..696	CDD:275368
		C2H2 Zn finger	704..722	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446681
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	0.930