DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2116 and ZNF707

DIOPT Version :9

Sequence 1:NP_572444.2 Gene:CG2116 / 31735 FlyBaseID:FBgn0030003 Length:598 Species:Drosophila melanogaster
Sequence 2:NP_001094068.1 Gene:ZNF707 / 286075 HGNCID:27815 Length:371 Species:Homo sapiens


Alignment Length:326 Identity:88/326 - (26%)
Similarity:126/326 - (38%) Gaps:45/326 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly   138 DNERVEEDLDMYPPSSPSLPPSPPRPPSPVVQPASKARNSARQIALR--SFVSQKNNDDDDGSVK 200
            |.||.|.......|...:...:.|:.|......|.|..:..|:.|..  ||......|.|||.:.
Human    70 DRERPEFQAVQRGPRPGARKSADPKRPCDHPAWAHKKTHVRRERAREGSSFRKGFRLDTDDGQLP 134

  Fly   201 EVKPSE----------KMLEEFKG--PRRYMLFDDLIATIVDFDEDSTPLVEFSMISDIMDEKLP 253
            ...|..          ::|.:..|  |.|.             :......||.|.|         
Human   135 RAAPERTDAKPTAFPCQVLTQRCGRRPGRR-------------ERRKQRAVELSFI--------- 177

  Fly   254 VECGICPDVMH-KSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCELCT 317
              ||.|...:. .|:|..|...|  .||..:.|..|.:|:|....|..|.:.|...:|:.||.|.
Human   178 --CGTCGKALSCHSRLLAHQTVH--TGTKAFECPECGQTFRWASNLQRHQKNHTREKPFCCEACG 238

  Fly   318 LYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYYKNFS 382
            ..||.|..|..|.:.....:.:.|..|||.|.|.:.|.|| :..|..:|.|.|..|.||:....:
Human   239 QAFSLKDRLAQHRKVHTEHRPYSCGDCGKAFKQKSNLLRH-QLVHTGERPFYCADCGKAFRTKEN 302

  Fly   383 LQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFDAHKR 447
            |..|.| ||.|: :...|..||...|.....:.||: :||::..|.|..|.:.|..:.:|..|:|
Human   303 LSHHQR-VHSGE-KPYTCAECGKSFRWPKGFSIHRR-LHLTKRFYECGHCGKGFRHLGFFTRHQR 364

  Fly   448 S 448
            :
Human   365 T 365

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2116NP_572444.2 C2H2 Zn finger 256..275 CDD:275368 6/19 (32%)
C2H2 Zn finger 285..305 CDD:275368 6/19 (32%)
PHA00733 <308..357 CDD:177301 16/48 (33%)
C2H2 Zn finger 313..334 CDD:275368 8/20 (40%)
C2H2 Zn finger 341..362 CDD:275368 9/20 (45%)
C2H2 Zn finger 370..388 CDD:275368 6/17 (35%)
C2H2 Zn finger 400..418 CDD:275370 5/17 (29%)
C2H2 Zn finger 429..447 CDD:275368 5/17 (29%)
ZNF707NP_001094068.1 KRAB 8..68 CDD:214630
KRAB 8..47 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 71..143 17/71 (24%)
C2H2 Zn finger 178..198 CDD:275368 6/19 (32%)
COG5048 <187..366 CDD:227381 59/185 (32%)
C2H2 Zn finger 206..226 CDD:275368 6/19 (32%)
zf-H2C2_2 218..242 CDD:290200 7/23 (30%)
C2H2 Zn finger 234..254 CDD:275368 8/19 (42%)
zf-C2H2 260..282 CDD:278523 9/22 (41%)
C2H2 Zn finger 262..282 CDD:275368 9/20 (45%)
zf-H2C2_2 274..299 CDD:290200 10/25 (40%)
C2H2 Zn finger 290..310 CDD:275368 7/20 (35%)
zf-H2C2_2 302..325 CDD:290200 9/24 (38%)
C2H2 Zn finger 318..338 CDD:275368 6/20 (30%)
C2H2 Zn finger 346..366 CDD:275368 6/20 (30%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 104 1.000 Inparanoid score I4954
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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