DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and Zfp668

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_001349118.1	Gene:	Zfp668 / 244219	MGIID:	2442943	Length:	619	Species:	Mus musculus

Alignment Length:	216	Identity:	66/216 - (30%)
Similarity:	100/216 - (46%)	Gaps:	13/216 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly   251 KLPVECGICPDVMHK-SKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCE 314
            :||..|..||..... |||..|.:.|  .|...|||..|.:::.|......|.|.|.|:|||.||
Mouse   137 ELPFRCTHCPKAYGTLSKLKIHQRGH--TGERPYACPDCGKSFADPSVFRKHRRTHAGLRPYSCE 199

  Fly   315 LCTLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYYK 379
            .|...::..:|||.|.:....|:..:|..|||:|::::.|..| :..|..::.::|..|.|.:.:
Mouse   200 RCGKAYAELKDLRNHERSHTGERPFLCSECGKSFSRSSSLTCH-QRIHAAQKPYRCPACGKGFTQ 263

  Fly   380 NFSLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFDA 444
            ..|.|.|.| .|.|::..| ||.||....|.....||:: .|.....|.|..|.::|...:....
Mouse   264 LSSYQSHER-THSGEKPFL-CPRCGRMFSDPSSFRRHQR-AHEGVKPYRCEKCGKDFRQPADLAM 325

  Fly   445 HK------RSIQCRSNTRRFV 459
            |:      |..:|....:.||
Mouse   326 HRRVHTGDRPFKCLQCDKTFV 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	7/19 (37%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		PHA00733	<308..357	CDD:177301	17/48 (35%)
		C2H2 Zn finger	313..334	CDD:275368	7/20 (35%)
		C2H2 Zn finger	341..362	CDD:275368	7/20 (35%)
		C2H2 Zn finger	370..388	CDD:275368	6/17 (35%)
		C2H2 Zn finger	400..418	CDD:275370	7/17 (41%)
		C2H2 Zn finger	429..447	CDD:275368	4/23 (17%)
Zfp668	NP_001349118.1	C2H2 Zn finger	24..44	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	36..74
		COG5048	65..419	CDD:227381	66/216 (31%)
		C2H2 Zn finger	86..106	CDD:275368
		C2H2 Zn finger	114..134	CDD:275368
		C2H2 Zn finger	142..162	CDD:275368	7/19 (37%)
		C2H2 Zn finger	170..190	CDD:275368	5/19 (26%)
		C2H2 Zn finger	198..218	CDD:275368	7/19 (37%)
		C2H2 Zn finger	226..246	CDD:275368	7/20 (35%)
		COG5048	248..598	CDD:227381	27/102 (26%)
		C2H2 Zn finger	254..274	CDD:275368	7/20 (35%)
		C2H2 Zn finger	282..302	CDD:275368	7/20 (35%)
		C2H2 Zn finger	310..330	CDD:275368	4/19 (21%)
		C2H2 Zn finger	338..358	CDD:275368	3/9 (33%)
		C2H2 Zn finger	366..386	CDD:275368
		C2H2 Zn finger	394..414	CDD:275368
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	491..513
		C2H2 Zn finger	518..538	CDD:275368
		C2H2 Zn finger	546..566	CDD:275368
		C2H2 Zn finger	574..594	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910