DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and sdz-12

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_494634.1	Gene:	sdz-12 / 184388	WormBaseID:	WBGene00017406	Length:	330	Species:	Caenorhabditis elegans

Alignment Length:	248	Identity:	59/248 - (23%)
Similarity:	103/248 - (41%)	Gaps:	44/248 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly   313 CELCTLYFSTKQDLRVHNQRRHL----------EKEHICEVCGKTFAQNTQLKRHREATHEKKRR 367
            |::|...|:.::.||.|  .:|:          ..:..||.|.|.|.....|||| :.||...:.
Worm    29 CQVCKRKFANQKTLRTH--MKHITCRPGRSNVVNHKFRCENCEKQFTNKPNLKRH-QITHSGSKS 90

  Fly   368 FQCEYCQKAYYKNFSLQEHIRNVHMGKRRMLKCPF--CGMQC-----RDAHKMARHRKEMHLSQG 425
            .:|..||:.:::...||.|:.| |:.:|....||.  |.||.     .:.|.:..|    |.|..
Worm    91 KKCSTCQRTFFREDQLQRHLHN-HLKERSHFDCPVLNCSMQFVFYEGVENHLVNHH----HFSYS 150

  Fly   426 -TYVCHLCQEEFTD-----ISYFDAHKRSIQ----CRSNTRRFVNADGNREGSDSE--SISGRNM 478
             :..|..|.:.|..     :.|...||.:::    ..:::.|......:..||...  :||.:..
Worm   151 ESAPCGKCHKLFGSPRHLLVHYHFDHKEALRSSAPAPTSSARLSPITVSTSGSPRAQLAISPQEK 215

  Fly   479 NGQDDDYD-GMGPLQEEYDEDDGLLVEDNQPEEQGSPSNRQYLDESEQQYVQL 530
            ..|....: |..|:.||:.|.:...:.:.  ::|.||:    |..:|.::..|
Worm   216 PPQKLSINLGTSPMIEEFCEQNSATLPNT--DQQLSPT----LSPNEPRFRNL 262

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368
		C2H2 Zn finger	285..305	CDD:275368
		PHA00733	<308..357	CDD:177301	14/53 (26%)
		C2H2 Zn finger	313..334	CDD:275368	6/20 (30%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		C2H2 Zn finger	370..388	CDD:275368	6/17 (35%)
		C2H2 Zn finger	400..418	CDD:275370	7/24 (29%)
		C2H2 Zn finger	429..447	CDD:275368	5/22 (23%)
sdz-12	NP_494634.1	SFP1	<25..86	CDD:227516	17/59 (29%)
		C2H2 Zn finger	29..48	CDD:275368	6/20 (30%)
		COG5236	<32..>197	CDD:227561	42/172 (24%)
		C2H2 Zn finger	65..85	CDD:275368	9/20 (45%)
		C2H2 Zn finger	93..113	CDD:275368	7/20 (35%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000