DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2116 and ZNF679

DIOPT Version :9

Sequence 1:NP_572444.2 Gene:CG2116 / 31735 FlyBaseID:FBgn0030003 Length:598 Species:Drosophila melanogaster
Sequence 2:NP_699194.2 Gene:ZNF679 / 168417 HGNCID:28650 Length:411 Species:Homo sapiens


Alignment Length:213 Identity:63/213 - (29%)
Similarity:96/213 - (45%) Gaps:13/213 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly   241 FSMISDIMDEKL------PVECGICPDVMH-KSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYL 298
            |.|:|.:...::      ..:|..|....: .|.||||.:.|  .|...|.|..|.:.:.....|
Human   193 FCMVSQLHQHQIIHTRENSYQCEECGKPFNCSSTLSKHKRIH--TGEKPYRCEECGKAFTWSSTL 255

  Fly   299 AGHARRHMGIRPYVCELCTLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHE 363
            ..|.|.|.|.:||.||.|...||....|..|.:....||.:.||.|||.|:.::.|..|:. .|.
Human   256 TKHRRIHTGEKPYTCEECGQAFSRSSTLANHKRIHTGEKPYTCEECGKAFSLSSSLTYHKR-IHT 319

  Fly   364 KKRRFQCEYCQKAYYKNFSLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYV 428
            .::.:.||.|.||:..:.:|::| :.:|.|: :..||..||.....:..:..| |.:|..:..|.
Human   320 GEKPYTCEECGKAFNCSSTLKKH-KIIHTGE-KPYKCKECGKAFAFSSTLNTH-KRIHTGEEPYK 381

  Fly   429 CHLCQEEFTDISYFDAHK 446
            |..|.:.|...|....||
Human   382 CEECDKAFKWSSSLANHK 399

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2116NP_572444.2 C2H2 Zn finger 256..275 CDD:275368 7/19 (37%)
C2H2 Zn finger 285..305 CDD:275368 5/19 (26%)
PHA00733 <308..357 CDD:177301 18/48 (38%)
C2H2 Zn finger 313..334 CDD:275368 7/20 (35%)
C2H2 Zn finger 341..362 CDD:275368 8/20 (40%)
C2H2 Zn finger 370..388 CDD:275368 7/17 (41%)
C2H2 Zn finger 400..418 CDD:275370 4/17 (24%)
C2H2 Zn finger 429..447 CDD:275368 6/18 (33%)
ZNF679NP_699194.2 KRAB 16..76 CDD:214630
KRAB 16..55 CDD:279668
C2H2 Zn finger 159..178 CDD:275368
C2H2 Zn finger 186..206 CDD:275368 3/12 (25%)
C2H2 Zn finger 214..234 CDD:275368 7/19 (37%)
zf-H2C2_2 227..250 CDD:290200 9/24 (38%)
COG5048 <238..401 CDD:227381 51/166 (31%)
C2H2 Zn finger 242..262 CDD:275368 5/19 (26%)
zf-H2C2_2 255..279 CDD:290200 11/23 (48%)
C2H2 Zn finger 270..290 CDD:275368 7/19 (37%)
zf-H2C2_2 283..306 CDD:290200 9/22 (41%)
C2H2 Zn finger 298..318 CDD:275368 8/20 (40%)
zf-H2C2_2 310..335 CDD:290200 8/25 (32%)
C2H2 Zn finger 326..346 CDD:275368 7/20 (35%)
zf-H2C2_2 339..362 CDD:290200 8/24 (33%)
C2H2 Zn finger 354..374 CDD:275368 5/20 (25%)
zf-H2C2_2 367..390 CDD:290200 6/23 (26%)
C2H2 Zn finger 382..402 CDD:275368 6/18 (33%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 1 1.050 104 1.000 Inparanoid score I4954
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.050

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