Protein Alignment CG2116 and ZNF785

DIOPT Version :9

• Sequence 1: NP_572444.2
• Gene: CG2116 / 31735
• FlyBaseID: FBgn0030003
• Length: 598
• Species: Drosophila melanogaster
• Sequence 2: XP_011544054.1
• Gene: ZNF785 / 146540
• HGNCID: 26496
• Length: 418
• Species: Homo sapiens
• Alignment Length: 401
• Identity: 89/401 - (22%)
• Similarity: 136/401 - (33%)
• Gaps: 121/401 - (30%)

  Fly   111 VEPEMEQEADYGDYGDYEHEPSYGH-------PRDNERVEEDLDMYPPSSPSLPPSPPRPPSPVV 168
            ||.|:|..:......|.|...::..       .||....:|.|...|
Human    94 VEGEVEAWSPEAQDPDGESSAAFSRGQGQEAGSRDGNEEKERLKKCP------------------ 140

  Fly   169 QPASKARNSARQIALRSFVSQKNNDDDDGSVKEVKPSEKMLEEFKGPRRYMLFDDLIATIVDFDE 233
                |.:..|.::|                |||..|| ....||..||:
Human   141 ----KQKEVAHEVA----------------VKEWWPS-VACPEFCNPRQ---------------- 168

  Fly   234 DSTPLVEFSMISDIMDEKLPVECGICPDVMHKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYL 298
              :|:..:  :.|.:..:||..   |||                          |...:.....|
Human   169 --SPMNPW--LKDTLTRRLPHS---CPD--------------------------CGRNFSYPSLL 200

  Fly   299 AGHARRHMGIRPYVCELCTLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHE 363
            |.|.|.|.|.||:.|..|...||.::.|..|......||.:.|..||:.|.|...|..||.| |.
Human   201 ASHQRVHSGERPFSCGQCQARFSQRRYLLQHQFIHTGEKPYPCPDCGRRFRQRGSLAIHRRA-HT 264

  Fly   364 KKRRFQCEYCQKAYYKNFSLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYV 428
            .::.:.|..|:..:...:.|..|.|. |.|: :...||.|.::......:|.||: :|..:..|.
Human   265 GEKPYACSDCKSRFTYPYLLAIHQRK-HTGE-KPYSCPDCSLRFAYTSLLAIHRR-IHTGEKPYP 326

  Fly   429 CHLCQEEFTDISYFDAHKR---------SIQCRSNTRRFVNADGNR--EGSDSE------SISGR 476
            |..|...||..|...:|:|         .::|....:|....:.:|  ..|.||      ::.||
Human   327 CPDCGRRFTYSSLLLSHRRIHSDSRPFPCVECGKGFKRKTALEAHRWIHRSCSERRAWQQAVVGR 391

  Fly   477 N-----MNGQD 482
            :     :.|:|
Human   392 SEPIPVLGGKD 402

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	3/18 (17%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		PHA00733	<308..357	CDD:177301	16/48 (33%)
		C2H2 Zn finger	313..334	CDD:275368	6/20 (30%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		C2H2 Zn finger	370..388	CDD:275368	4/17 (24%)
		C2H2 Zn finger	400..418	CDD:275370	5/17 (29%)
		C2H2 Zn finger	429..447	CDD:275368	6/17 (35%)
ZNF785	XP_011544054.1	KRAB	29..102	CDD:214630	4/7 (57%)
		COG5048	<156..372	CDD:227381	64/269 (24%)
		C2H2 Zn finger	187..207	CDD:275368	8/45 (18%)
		C2H2 Zn finger	215..235	CDD:275368	6/19 (32%)
		C2H2 Zn finger	243..263	CDD:275368	9/20 (45%)
		C2H2 Zn finger	271..291	CDD:275368	5/20 (25%)
		C2H2 Zn finger	299..319	CDD:275368	6/20 (30%)
		C2H2 Zn finger	327..347	CDD:275368	7/19 (37%)
		C2H2 Zn finger	355..375	CDD:275368	3/19 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	104	1.000	Inparanoid score	I4954
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	1.050