DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2116 and AgaP_AGAP009662

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	XP_318706.4	Gene:	AgaP_AGAP009662 / 1279046	VectorBaseID:	AGAP009662	Length:	556	Species:	Anopheles gambiae

Alignment Length:	309	Identity:	83/309 - (26%)
Similarity:	126/309 - (40%)	Gaps:	47/309 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 PVECGICPDVMH-KSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCELC 316
            |.:|.:|..... .::|.:|::||  .|...:.|.:|.:.:...:.|..|.|.|...|||.||:|
Mosquito    73 PYQCDVCKKTFAVPARLVRHYRTH--TGERPFECEFCHKMFSVKENLQVHRRIHTKERPYKCEIC 135

  Fly   317 TLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQC--EYCQKAYYK 379
            ...|.....|..|.:....|:.|.|.||||||.|:.||..|.. ||..::.::|  |.|.|.:..
Mosquito   136 GRAFEHSGKLHRHMRIHTGERPHKCNVCGKTFIQSGQLVIHMR-THTGEKPYKCPVEGCGKGFTC 199

  Fly   380 NFSLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFDA 444
            :..|:.|.| .|.|: :...|..|.......|.:..||.: |.....|.|.:|.|.|......:|
Mosquito   200 SKQLKVHSR-THTGE-KPYHCDICFRDFGYNHVLKLHRVQ-HYGAKCYKCTICDETFKSKKEMEA 261

  Fly   445 HKRSIQCRSN---------------------TRRFVNADGNREGS---DSESISGRNMNGQDDDY 485
            |   |:..:|                     ....|:..|. |||   .|.::.|.|..||....
Mosquito   262 H---IKGHANELPDDEEAAAAAAASDAGGACKLEDVSTSGT-EGSIKLSSSALEGANEAGQQVGA 322

  Fly   486 DGMGPLQEEYDEDDGLLVEDNQPEEQGSPSNRQYLDESEQQYVQLSDYD 534
            |      ||.:||:    |:|..||..:..:.........:.::.|.:|
Mosquito   323 D------EEEEEDE----EENDEEEDETTDDGDRKQMPRYESIEPSSFD 361

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	4/19 (21%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		PHA00733	<308..357	CDD:177301	21/48 (44%)
		C2H2 Zn finger	313..334	CDD:275368	6/20 (30%)
		C2H2 Zn finger	341..362	CDD:275368	11/20 (55%)
		C2H2 Zn finger	370..388	CDD:275368	6/19 (32%)
		C2H2 Zn finger	400..418	CDD:275370	4/17 (24%)
		C2H2 Zn finger	429..447	CDD:275368	6/17 (35%)
AgaP_AGAP009662	XP_318706.4	C2H2 Zn finger	12..32	CDD:275368
		C2H2 Zn finger	76..96	CDD:275368	4/19 (21%)
		zf-H2C2_2	89..112	CDD:290200	7/24 (29%)
		C2H2 Zn finger	104..124	CDD:275368	5/19 (26%)
		zf-H2C2_2	116..141	CDD:290200	11/24 (46%)
		COG5048	<129..271	CDD:227381	47/148 (32%)
		C2H2 Zn finger	132..152	CDD:275368	6/19 (32%)
		zf-H2C2_2	147..169	CDD:290200	10/21 (48%)
		C2H2 Zn finger	160..180	CDD:275368	11/20 (55%)
		zf-H2C2_2	173..199	CDD:290200	8/26 (31%)
		C2H2 Zn finger	188..210	CDD:275368	7/22 (32%)
		zf-H2C2_2	203..227	CDD:290200	7/25 (28%)
		C2H2 Zn finger	218..238	CDD:275368	5/20 (25%)
		C2H2 Zn finger	246..266	CDD:275368	7/22 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910