DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and Gm14444

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_001365634.1	Gene:	Gm14444 / 105244402	MGIID:	3652325	Length:	394	Species:	Mus musculus

Alignment Length:	236	Identity:	69/236 - (29%)
Similarity:	104/236 - (44%)	Gaps:	20/236 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   253 PVECGICPDVM-HKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCELC 316
            |.||..|.... |.|.|..|.:||  .....|.|..|.:.:....:|..|.|.|.|.:||.|:.|
Mouse   154 PYECKQCGKAFAHSSHLHIHERTH--TREKPYECKQCGKAFSQSSHLQIHKRTHTGEKPYECKQC 216

  Fly   317 TLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYYKNF 381
            ...|:....||:|.|....||.:.|:.|||.||.:..|::|:: ||..::.::|:.|.||:.:..
Mouse   217 GKAFAQSSHLRIHKQTHTGEKPYECKQCGKGFAGSGDLQKHKQ-THTGEKPYECKQCGKAFSRKS 280

  Fly   382 SLQEHIRNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFDAHK 446
            .||:| :..|.|: :..:|..||.....:..:..| |..|..:..|.|..|.:.|...|....||
Mouse   281 DLQKH-KRTHTGE-KPYECKQCGKAFAQSSTLQIH-KRTHTGEKPYECKQCGKAFAGSSGLQCHK 342

  Fly   447 RS------IQCRSNTRRFVNADGNREGSDSESISGRNMNGQ 481
            ||      .:|....:.|       |||.....:.|....:
Mouse   343 RSHTGETPYECNQGGKPF-------EGSSGLEYNNRTQTAE 376

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	6/19 (32%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		PHA00733	<308..357	CDD:177301	18/48 (38%)
		C2H2 Zn finger	313..334	CDD:275368	7/20 (35%)
		C2H2 Zn finger	341..362	CDD:275368	8/20 (40%)
		C2H2 Zn finger	370..388	CDD:275368	7/17 (41%)
		C2H2 Zn finger	400..418	CDD:275370	4/17 (24%)
		C2H2 Zn finger	429..447	CDD:275368	5/17 (29%)
Gm14444	NP_001365634.1	C2H2 Zn finger	48..65	CDD:275368
		COG5048	<56..231	CDD:227381	26/78 (33%)
		C2H2 Zn finger	73..93	CDD:275368
		C2H2 Zn finger	101..121	CDD:275368
		C2H2 Zn finger	129..149	CDD:275368
		C2H2 Zn finger	157..177	CDD:275368	6/19 (32%)
		COG5048	<167..337	CDD:227381	53/175 (30%)
		C2H2 Zn finger	185..205	CDD:275368	5/19 (26%)
		C2H2 Zn finger	213..233	CDD:275368	7/19 (37%)
		C2H2 Zn finger	241..261	CDD:275368	8/20 (40%)
		C2H2 Zn finger	269..289	CDD:275368	7/20 (35%)
		C2H2 Zn finger	297..317	CDD:275368	5/20 (25%)
		C2H2 Zn finger	325..345	CDD:275368	7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910