DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2116 and zscan2

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	XP_002943732.2	Gene:	zscan2 / 100486661	XenbaseID:	XB-GENE-6033591	Length:	491	Species:	Xenopus tropicalis

Alignment Length:	442	Identity:	110/442 - (24%)
Similarity:	174/442 - (39%)	Gaps:	86/442 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 VEPEME-QEADYGDYGDYEHEPSYGHPRDNERVEEDLDMYPPSSPSLPPSPPRP-PSPVV----- 168
            :||... ..:|..:.||.|..|... |..:.|..||:     |.|.||.:..|. |.|..
Frog     1 MEPNFRGSGSDMQERGDPEESPLQS-PGTDMRCLEDI-----SLPDLPETTERDVPKPCAGEQSI 59

  Fly   169 ----QPASKARNSARQIALRSFVSQKNNDDDDGSVKEVKPSEKMLEEFKGPR----RYMLFDDLI 225
                :|....||.:|....|..:....:.|..||:  ||| |.|.|....|.    ..:.....:
Frog    60 RRRRKPVKTHRNPSRSSPERLLLDVTISGDVPGSL--VKP-ECMKESAPSPHGTPWSTLSARSDV 121

  Fly   226 ATIVDFDEDSTP--------LVEFSMISDIMDEKL------------------------PVECGI 258
            .:...|..|..|        :...|..::..::.|                        |..|..
Frog   122 PSASSFSTDLYPQRDPFTYIMPPESAANETSEQHLTAGSQTLCTNRSAKSQKKTSTKVKPFLCTT 186

  Fly   259 C-PDVMHKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYVCELCTLYFST 322
            | .....||.|.:||:.|  .|...:.||.|.:::..|..|..|.:.|.|.:|:.|..|...||.
Frog   187 CGKRFSQKSLLIQHHRNH--TGERPFPCIECGKSFTSCSLLIRHHKIHTGEKPFACSDCGKRFSE 249

  Fly   323 KQDLRVHNQRRHL-EKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQKAYYKNFSLQEH 386
            ...| |.:||.|. |:.:.|..|||:|:::::|..| :.||..:|.:.|..|.    |:||::.|
Frog   250 SSQL-VRHQRTHTGERPYTCIECGKSFSESSKLVIH-QRTHTGERPYSCSDCG----KSFSVRSH 308

  Fly   387 I---RNVHMGKRRMLKCPFCGMQCRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFDAHKR- 447
            :   :..|.|: |...|..||....::.|:..|:: :|..:..|.|..|.:.|:..|....|:|
Frog   309 LITHKRTHTGE-RPYTCNDCGKSFSESSKLVMHQR-IHTGEKPYTCAACGKSFSQRSVLVTHQRI 371

  Fly   448 -----SIQCRSNTRRF---VNADGNREGSDSES-----ISGRNMNGQDDDYD 486
                 ...|....:.|   |..|.:|....:|.     |.|:|.: ::.||:
Frog   372 HTGEKPYTCPECGKSFIDKVGCDRHRVTHSNEKPFQCLICGKNFS-RNSDYN 422

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	7/19 (37%)
		C2H2 Zn finger	285..305	CDD:275368	6/19 (32%)
		PHA00733	<308..357	CDD:177301	17/49 (35%)
		C2H2 Zn finger	313..334	CDD:275368	8/20 (40%)
		C2H2 Zn finger	341..362	CDD:275368	7/20 (35%)
		C2H2 Zn finger	370..388	CDD:275368	6/20 (30%)
		C2H2 Zn finger	400..418	CDD:275370	5/17 (29%)
		C2H2 Zn finger	429..447	CDD:275368	5/17 (29%)
zscan2	XP_002943732.2	COG5048	<68..314	CDD:227381	64/256 (25%)
		C2H2 Zn finger	184..204	CDD:275368	7/19 (37%)
		zf-H2C2_2	197..221	CDD:290200	8/25 (32%)
		COG5048	208..>471	CDD:227381	62/224 (28%)
		C2H2 Zn finger	212..232	CDD:275368	6/19 (32%)
		zf-H2C2_2	225..248	CDD:290200	7/22 (32%)
		C2H2 Zn finger	240..260	CDD:275368	8/20 (40%)
		zf-H2C2_2	253..276	CDD:290200	10/23 (43%)
		C2H2 Zn finger	268..288	CDD:275368	7/20 (35%)
		zf-H2C2_2	281..304	CDD:290200	8/27 (30%)
		C2H2 Zn finger	296..316	CDD:275368	6/23 (26%)
		zf-H2C2_2	308..332	CDD:290200	7/24 (29%)
		C2H2 Zn finger	324..344	CDD:275368	5/20 (25%)
		zf-H2C2_2	337..361	CDD:290200	6/24 (25%)
		C2H2 Zn finger	352..372	CDD:275368	6/19 (32%)
		zf-H2C2_2	365..387	CDD:290200	3/21 (14%)
		C2H2 Zn finger	380..400	CDD:275368	5/19 (26%)
		zf-C2H2	406..428	CDD:278523	5/18 (28%)
		C2H2 Zn finger	408..428	CDD:275368	5/16 (31%)
		zf-H2C2_2	420..444	CDD:290200	2/3 (67%)
		C2H2 Zn finger	436..456	CDD:275368
		zf-H2C2_2	449..471	CDD:290200
		C2H2 Zn finger	464..484	CDD:275368
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910