DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2116 and znf1147

DIOPT Version :9

Sequence 1:	NP_572444.2	Gene:	CG2116 / 31735	FlyBaseID:	FBgn0030003	Length:	598	Species:	Drosophila melanogaster
Sequence 2:	NP_001108581.1	Gene:	znf1147 / 100141494	ZFINID:	ZDB-GENE-080218-13	Length:	260	Species:	Danio rerio

Alignment Length:	285	Identity:	71/285 - (24%)
Similarity:	121/285 - (42%)	Gaps:	60/285 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 SFVSQKNND---DDDGSVKE---VKPSEKML--EEFKGPRRYMLFDDLIATIVDFDEDSTPLVEF 241
            :|:.:::.|   ::..:||:   .:.|::|:  ||..|..             :.||.    .:|
Zfish     2 AFIKEESEDVKIEETFTVKQEDLQEQSDRMVLKEETHGQN-------------EIDEK----WQF 49

  Fly   242 SMISDIMDEKLPV--------------------ECGIC-PDVMHKSKLSKHHKTHLVPGTNRYAC 285
            ....:|..::.|.                    .|.:| .....||.|..|.:.|  .|...|.|
Zfish    50 EKPQEITTDEKPTLTKKTLSHGRPRKSKSGCNFSCKLCSKSFSQKSNLDVHMRVH--TGEKPYTC 112

  Fly   286 IYCTETYRDCKYLAGHARRHMGIRPYVCELCTLYFSTKQDLRVHNQRRHLEKEHICEVCGKTFAQ 350
            ..|.:::...:.|..|.|.|.|.:|:.|:.|...||.|.:|.:|.:....||.:.||.|||:|:|
Zfish   113 EQCGQSFSQKQCLKTHMRIHTGEKPFSCKQCGKSFSQKPNLDIHMRVHTGEKPYTCEQCGKSFSQ 177

  Fly   351 NTQLKRHREATHEKKRRFQCEYCQKAYYKNFSLQEHIRNVHMGKRRMLKCPFCGMQCRDA----H 411
            ....|.|.. .|..:|.:.|:.|.|::....:|:.|:| :|.|::     ||...|||.:    .
Zfish   178 KQSFKSHMR-IHTGERPYTCQQCGKSFRHARNLEVHMR-IHTGEK-----PFSCKQCRKSLSKKL 235

  Fly   412 KMARHRKEMHLSQGTYVCHLCQEEF 436
            .:..|.: :|..:..|.|..|.:||
Zfish   236 NLIAHMR-VHTMEKPYTCEQCGKEF 259

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2116	NP_572444.2	C2H2 Zn finger	256..275	CDD:275368	6/19 (32%)
		C2H2 Zn finger	285..305	CDD:275368	5/19 (26%)
		PHA00733	<308..357	CDD:177301	18/48 (38%)
		C2H2 Zn finger	313..334	CDD:275368	7/20 (35%)
		C2H2 Zn finger	341..362	CDD:275368	9/20 (45%)
		C2H2 Zn finger	370..388	CDD:275368	5/17 (29%)
		C2H2 Zn finger	400..418	CDD:275370	6/21 (29%)
		C2H2 Zn finger	429..447	CDD:275368	4/8 (50%)
znf1147	NP_001108581.1	zf-C2H2	82..104	CDD:278523	6/21 (29%)
		C2H2 Zn finger	84..104	CDD:275368	6/19 (32%)
		COG5048	<86..257	CDD:227381	54/180 (30%)
		zf-H2C2_2	96..121	CDD:290200	7/26 (27%)
		C2H2 Zn finger	112..132	CDD:275368	5/19 (26%)
		zf-H2C2_2	125..149	CDD:290200	9/23 (39%)
		C2H2 Zn finger	140..160	CDD:275368	7/19 (37%)
		zf-H2C2_2	152..177	CDD:290200	10/24 (42%)
		C2H2 Zn finger	168..188	CDD:275368	9/20 (45%)
		zf-H2C2_2	180..205	CDD:290200	7/25 (28%)
		C2H2 Zn finger	196..216	CDD:275368	6/20 (30%)
		zf-H2C2_2	208..230	CDD:290200	10/27 (37%)
		C2H2 Zn finger	224..244	CDD:275368	4/20 (20%)
		zf-H2C2_2	236..259	CDD:290200	5/23 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910