DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG2116 and Zbtb48

DIOPT Version :9

Sequence 1:NP_572444.2 Gene:CG2116 / 31735 FlyBaseID:FBgn0030003 Length:598 Species:Drosophila melanogaster
Sequence 2:XP_017175372.1 Gene:Zbtb48 / 100090 MGIID:2140248 Length:767 Species:Mus musculus


Alignment Length:638 Identity:119/638 - (18%)
Similarity:192/638 - (30%) Gaps:248/638 - (38%)


- Green bases have known domain annotations that are detailed below.


  Fly    79 VGSRVKDLTD-DEQMPQFVVRELDMSEVGDLVEVEPEMEQEADYGDYGDYEHEPSYGHPRDNERV 142
            |.|.:|:.|| ||:.   |.|.|.::.|          :||                 |||.|:.
Mouse   165 VKSHLKEPTDLDEEE---VFRTLSLASV----------DQE-----------------PRDTEQP 199

  Fly   143 EEDLDMYPPS-----------SPSLPPSP---------PRPPSPVVQPASKARNSARQIALRSFV 187
            :    :..|:           :.:|.|||         ..||.|.....:..:..:.:..    |
Mouse   200 Q----LGTPAQSTTAFLCGKLTQALKPSPSEDKESEDCKEPPRPFEAGGAPLQGESNEWE----V 256

  Fly   188 SQKNNDDDDGSVKEVKPSEKMLEEFKGPRRYMLFDDLIATIVDFDEDSTP-LVEFSMISDIMDEK 251
            ..:..||.||..  |...|.:|...|            :.::.....:.| |...|:.::..|.:
Mouse   257 VVQVEDDRDGDY--VSEPETVLTRRK------------SKVIRKPCAAEPALGAGSLTAEPTDSR 307

  Fly   252 ----LPVECGICPDVMHKSKLSKHHKTHLVPGTNRYACIYCTETYRDCKYLAGHARRHMGIRPYV 312
                :||||..|    ||..|||:                         ||..|.|:|.|.:|:.
Mouse   308 KGAAVPVECPTC----HKKFLSKY-------------------------YLKVHNRKHTGEKPFE 343

  Fly   313 CELCTLYFSTKQDLRVHNQRRHL---EKEHICEVCGKTFAQNTQLKRHREATHEKKRRFQCEYCQ 374
            |..|...:..|::|..|..|..:   |:...|.||.:||.:..:|:.|. .:|..:..::|..|.
Mouse   344 CPKCGKCYFRKENLLEHEARNCMNRSEQVFTCSVCQETFRRRMELRLHM-VSHTGEMPYKCSSCS 407

  Fly   375 KAYYKNFSLQEH----------------------------------------------------- 386
            :.:.:...||.|                                                     
Mouse   408 QQFMQKKDLQSHMIKLHGAPKPHAVSASQGWGSGGSGTAQSCPHLDVLPLPVSPTCSAPLVPSAS 472

  Fly   387 ---------------------IRNVHMGKRRMLKC-----PFCGMQ------------------- 406
                                 :||...|.|....|     |..||:                   
Mouse   473 CLGRSYSCTRLLSIVEKSSLCVRNAGTGPRAATDCRCTSRPSTGMKGLMSVSSAAMPSPRRPTST 537

  Fly   407 CRDAHKMARHRKEMHLSQGTYVCHLCQEEFTDISYFDAHKRSIQCRSNTRRFVNADGNREGSDSE 471
            |..||..||     .||..|.|                 .|....:....:.:.|.|.|:...|.
Mouse   538 CTCAHTPAR-----SLSSATSV-----------------GRPSAPKVRQAQPLLAPGLRQPLSST 580

  Fly   472 SISGRNMNGQDDDYDGMGPL-----QEEYDEDDGLLVEDNQPEEQGSPSNRQYLDESEQQYVQLS 531
            .....:::..:..:.|..|.     ::.:.|...||.......::|.|...|...::.:...||.
Mouse   581 LSPIASLDKHNRTHTGERPFSCEFCEQRFTEKGPLLRHVASRHQEGRPHFCQICGKTFKAVEQLR 645

  Fly   532 DYDDQHLLVENAVDAEDGGEDLDELLTEDQYFNAVQQHHQQHQQHHGRGQDYN 584
            .:..:|..|......|.|            |....|.|.::|.:.|.|.::||
Mouse   646 VHVRRHKGVRKFECTECG------------YKFTRQAHLRRHMEIHDRVENYN 686

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2116NP_572444.2 C2H2 Zn finger 256..275 CDD:275368 7/18 (39%)
C2H2 Zn finger 285..305 CDD:275368 4/19 (21%)
PHA00733 <308..357 CDD:177301 14/51 (27%)
C2H2 Zn finger 313..334 CDD:275368 6/20 (30%)
C2H2 Zn finger 341..362 CDD:275368 7/20 (35%)
C2H2 Zn finger 370..388 CDD:275368 5/91 (5%)
C2H2 Zn finger 400..418 CDD:275370 9/41 (22%)
C2H2 Zn finger 429..447 CDD:275368 0/17 (0%)
Zbtb48XP_017175372.1 BTB_POZ_ZBTB48_TZAP_KR3 38..145 CDD:349541
C2H2 Zn finger 316..336 CDD:275368 11/48 (23%)
zf-H2C2_2 328..351 CDD:372612 9/22 (41%)
C2H2 Zn finger 344..395 CDD:275368 14/51 (27%)
zf-H2C2_2 387..410 CDD:372612 5/23 (22%)
C2H2 Zn finger 403..424 CDD:275368 5/20 (25%)
PHA03247 <426..583 CDD:223021 22/178 (12%)
zf-H2C2_2 586..610 CDD:372612 2/23 (9%)
C2H2 Zn finger 602..623 CDD:275368 3/20 (15%)
C2H2 Zn finger 631..651 CDD:275368 3/19 (16%)
zf-H2C2_2 644..668 CDD:372612 6/35 (17%)
zf-C2H2 657..679 CDD:333835 6/33 (18%)
C2H2 Zn finger 659..679 CDD:275368 6/31 (19%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

Return to query results.
Submit another query.