DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cyr and m

DIOPT Version :9

Sequence 1:	NP_001285004.1	Gene:	cyr / 31733	FlyBaseID:	FBgn0030001	Length:	513	Species:	Drosophila melanogaster
Sequence 2:	NP_572747.1	Gene:	m / 44835	FlyBaseID:	FBgn0002577	Length:	682	Species:	Drosophila melanogaster

Alignment Length:	483	Identity:	103/483 - (21%)
Similarity:	156/483 - (32%)	Gaps:	178/483 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 LPLAIAIGVLHLPQFLCHAA---WTTRTPESFINDTTTTTTTTTTTTTKTMQIQAMQVNCSRELL 80
            |..:..|.:|||...|..|.   |....|:...|                  |.:::|.|.::.:
  Fly    14 LRFSSCIFILHLMFSLVIAGNELWPMERPDGMPN------------------IVSLEVMCGKDHM 60

  Fly    81 EMHLELSRPFRGLLYAKDFPLECR------ARGKDSTRLHLRIPTSGCGVRAEPLEDGSLEYTVR 139
            ::||..|.||.|::.:|....:.|      :.||  |....||..|.||.:  |..:|.. |...
  Fly    61 DVHLTFSHPFEGIVSSKGQHSDPRCVYVPPSTGK--TFFSFRISYSRCGTK--PDLNGQF-YENT 120

  Fly   140 VMLQKEQKLRQSTDILSSVRCQLPANAMGMPLPVLRQEKGHDRNARMRALAAAAAVPALGATSSI 204
            |::|.::.|.:..|....:||:...:          .||            .|:..|.:.|...:
  Fly   121 VVVQYDKDLLEVWDEAKRLRCEWFND----------YEK------------TASKPPMVIADLDV 163

  Fly   205 NQQQRETPRVRIWLEL------GGPNGTGSVEVGVATTLTVRAI--VPGNIGVRVVDCAALDGLG 261
            .|.......|..|:|:      ..|..:|.|.:|...||.| ||  ..|...:||..|.|.||.|
  Fly   164 IQLDFRGDNVDCWMEIQHGKGPWAPPVSGIVPLGSTLTLVV-AINDYRGEFDMRVKSCVASDGSG 227

  Fly   262 ESTQQLLDARGCPIDEQVMPALHTQHRPAEEGWSKQHEEDLVERTFAATFPAFKFPDRERLHVSC 326
            . ...|.|..||.:..:::........|         :|.....|: |.|.||||||...:|:.|
  Fly   228 H-VINLSDEFGCVLRPKMISRFLKARAP---------DERATVITY-AFFHAFKFPDALSVHIKC 281

  Fly   327 GVQLCKGKCPTLNCRLKTPPPALSAEQHLARIEVFNSLAVTAPQIEVDRLRYDRRHNMSGEDYAP 391
            .|::|:..|                                                      ..
  Fly   282 KVEICRHGC------------------------------------------------------LD 292

  Fly   392 HVRGQVMPGEGTLCLSISKLAISFCVLGLIFLVAVVVAIFSLIRSRRRERRHGAGLSLGLGVGLG 456
            |.:...:.|.|                                        .|:|.|||||:|||
  Fly   293 HCQNTGVGGGG----------------------------------------GGSGESLGLGLGLG 317

  Fly   457 IAGT----------STSNSSSRLHRDRA 474
            :...          :..:||:.|.||.|
  Fly   318 LTNANERKDVHMSDALGSSSNDLLRDLA 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cyr	NP_001285004.1	ZP	82..344	CDD:214579	71/275 (26%)
m	NP_572747.1	ZP	55..286	CDD:214579	70/269 (26%)
m	NP_572747.1	Zona_pellucida	<194..287	CDD:278526	33/104 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45473269
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR46560
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940