Protein Alignment CG2260 and UTP7

DIOPT Version :10

• Sequence 1: NP_572441.1
• Gene: CG2260 / 31732
• FlyBaseID: FBgn0030000
• Length: 609
• Species: Drosophila melanogaster
• Sequence 2: NP_011005.1
• Gene: UTP7 / 856815
• SGDID: S000000884
• Length: 554
• Species: Saccharomyces cerevisiae
• Alignment Length: 561
• Identity: 194/561 - (34%)
• Similarity: 294/561 - (52%)
• Gaps: 48/561 - (8%)

  Fly    71 KEELEARPKKNPIPKEILDKYSRGEQVQPKGVKTRHFKEQQTRKEVYLEY--ATEQAARTELLLQ 133
            :.:::.|..:|...:......::....|.|..|.|     ...|::..:|  |...||.|:.||.
Yeast     9 RRQIKERENQNKFERSTYTNNAKNNHTQTKDKKLR-----AGLKKIDEQYKKAVSSAAATDYLLP 68

  Fly   134 ETAGQLQAD-EGETTAEFRQSQIAENVDIQSSAKHFNLNM-EFGPYRMRYTKNGRHLLLGGKRGH 196
            |:.|.|:.: |.|.|.:.:||:|..:||:.::.|..:|:: |||||.::|.|||.|||:.|::||
Yeast    69 ESNGYLEPENELEKTFKVQQSEIKSSVDVSTANKALDLSLKEFGPYHIKYAKNGTHLLITGRKGH 133

  Fly   197 VAAFDWVTKRLHCEFNAMESVEDVQWLHVPTMYAVAQKSWVYFYDKKGTELHCIKRLNRVNRLDF 261
            ||:.||...:|..|....|:.....:|.....:|||||.:.:.||.:|||||.:|:......|||
Yeast   134 VASMDWRKGQLRAELFLNETCHSATYLQNEQYFAVAQKKYTFIYDHEGTELHRLKQHIEARHLDF 198

  Fly   262 LPYHFLLAAGNSAGYASWLDVSIGELVGNFNTGLGDIRMLRHNPRNGVLCIGGGRGVVSMWSPKV 326
            ||||:||......|:..:.|||.|:||....|..|....:..||.|.|:.:|...|.||:|||.:
Yeast   199 LPYHYLLVTAGETGWLKYHDVSTGQLVSELRTKAGPTMAMAQNPWNAVMHLGHSNGTVSLWSPSM 263

  Fly   327 REPLAKLLCHSTAMSALAVEPKGQYLVTAGLDRAVKVWDIRMLVHDKPLTHFQ-LRLPANELDVS 390
            .|||.|||.....::::|::..|.|:.|.|.||::|:||||   :.|.|...: |..|...:.:|
Yeast   264 PEPLVKLLSARGPVNSIAIDRSGYYMATTGADRSMKIWDIR---NFKQLHSVESLPTPGTNVSIS 325

  Fly   391 QRGMLALSQGTYLETYSDL--LSGG-----GSGDGT---RLPYIRQRCDAF----VHGLRFCPYE 441
            ..|:||||:|.::..:.|.  |||.     ||..|.   ..||:..   .|    |..|.|.|:|
Yeast   326 DTGLLALSRGPHVTLWKDALKLSGDSKPCFGSMGGNPHRNTPYMSH---LFAGNKVENLGFVPFE 387

  Fly   442 DVLGVSTAKGFQSLLVPGSGEPNFDAMEDNPYETSKQRREHEVHALLEKIPPELITLDPQEITGV 506
            |:|||....|..:|:|||:||.|:||:|.||:||.|||:|.||..||.|:|.:.|||||..|..|
Yeast   388 DLLGVGHQTGITNLIVPGAGEANYDALELNPFETKKQRQEQEVRTLLNKLPADTITLDPNSIGSV 452

  Fly   507 DAPTLQEKIDAKRKLFHLKAPRINMKSRHK-----------MKGR-GGTAKAARNK-QIVKDAKR 558
            |..:...:::||    .|....::..::.|           :||: .|.....|.| |.|.| :|
Yeast   453 DKRSSTIRLNAK----DLAQTTMDANNKAKTNSDIPDVKPDVKGKNSGLRSFLRKKTQNVID-ER 512

  Fly   559 KEFIAEVREAKKNVIKQHTADEVGAKGKAKTKAPRSVLDRF 599
            |..:.:..:.:||:.|::...:.|...:.........|.||
Yeast   513 KLRVQKQLDKEKNIRKRNHQIKQGLISEDHKDVIEEALSRF 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2260	NP_572441.1	WD40	<177..367	CDD:441893	77/189 (41%)
		WD40 repeat	181..210	CDD:293791	15/28 (54%)
		WD40 repeat	218..253	CDD:293791	14/34 (41%)
		WD40 repeat	256..292	CDD:293791	16/35 (46%)
		WD40 repeat	299..334	CDD:293791	15/34 (44%)
		WD40 repeat	340..376	CDD:293791	13/35 (37%)
		BING4CT	422..500	CDD:198101	40/81 (49%)
UTP7	NP_011005.1	WD40 repeat	116..149	CDD:293791	16/32 (50%)
		WD40 repeat	155..189	CDD:293791	13/33 (39%)
		WD40	157..333	CDD:475233	69/178 (39%)
		WD40 repeat	194..229	CDD:293791	16/34 (47%)
		WD40 repeat	236..272	CDD:293791	16/35 (46%)
		WD40 repeat	277..311	CDD:293791	14/36 (39%)
		BING4CT	367..445	CDD:462375	39/80 (49%)