DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2258 and dip1

DIOPT Version :9

Sequence 1:	NP_001285000.1	Gene:	CG2258 / 31729	FlyBaseID:	FBgn0029997	Length:	801	Species:	Drosophila melanogaster
Sequence 2:	NP_001342760.1	Gene:	dip1 / 2540504	PomBaseID:	SPBC24C6.10c	Length:	374	Species:	Schizosaccharomyces pombe

Alignment Length:	329	Identity:	74/329 - (22%)
Similarity:	142/329 - (43%)	Gaps:	72/329 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly   492 EDEEDIIQFLEELVEILINADESISCYEMSCDQYQMFINLVQYYQMETRWSIKRLLLKTFTAACH 556
            |:|:..:..::||:.|....:|    .|:...::..|||......:.|.:.::|.:.|...:..:
pombe    11 ENEKQFLAEIDELLTIPYEKNE----LEIGVSKFLSFINKYGEPYLITEFQLQRCMEKFLNSPLY 71

  Fly   557 -----------------------LDYIIVD--------------ILLTSVLP--LEIVEDMKTHF 582
                                   |.:||:.              :..|..:|  ::.::..|...
pombe    72 QLDENAVLSIFYDCFFFLKEQQTLKFIIIVFQSEIQENEYCLRLLASTGFIPVLIKAMKQFKDRS 136

  Fly   583 SNLDRFKQLVKMLTIIFSLGQPMPVNHQDYLGVHFASFLLEIV----EGNNPEVL--VDMVIALI 641
            .|: .|......|.:::.:.:...::..|.:.:. ..||:.:.    |..|.|.:  ..|.:..:
pombe   137 ENV-AFTSFRYALFLVYYICRSRRLSPTDLVAID-EYFLVNLFKTSEEAWNDEDMDSFGMCVLTL 199

  Fly   642 LAFNQQF------SEHTYNVIIEGMQNLPSAKV----FTEKLLLLLNREDDP-TRLLKHPNEHMN 695
            |:.|:||      |:.::.:....|..|.|:||    ::|.|:..||||.|| :|:|
pombe   200 LSINEQFMLVRLASKGSFEIANGIMDLLSSSKVDNGIYSEGLVFTLNREKDPRSRML-------- 256

  Fly   696 TVLRMFIDIFSHPDTAGMFYTNDIKVLIDIVVRQLSDL-DAGSTTRPCYLELCRRILRNTNYQEH 759
             :|:....:|:.|.|..:|||||:.|||||.:|::::: |..|..|..||::...:|.||..:..
pombe   257 -ILKQLFLLFTTPATYEIFYTNDLNVLIDIFIREINNIPDELSDLRYAYLQVLIPLLENTQVRHP 320

  Fly   760 QHRK 763
            .|.|
pombe   321 PHYK 324

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2258	NP_001285000.1	SH3_SPIN90	1..55	CDD:212783
		PHA03420	108..>188	CDD:177648
		DUF2013	631..766	CDD:286514	47/147 (32%)
dip1	NP_001342760.1	DUF2013	190..325	CDD:312809	46/144 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	63	1.000	Domainoid score	I2920
eggNOG	1	0.900	-	-		E1_KOG4035
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006257
OrthoInspector	1	1.000	-	-		oto101726
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13357
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5829
SonicParanoid	1	1.000	-	-		X4538
TreeFam	0	0.000	Not matched by this tool.
	8	7.940