DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2258 and Y55F3AM.5

DIOPT Version :9

Sequence 1:	NP_001285000.1	Gene:	CG2258 / 31729	FlyBaseID:	FBgn0029997	Length:	801	Species:	Drosophila melanogaster
Sequence 2:	NP_500021.4	Gene:	Y55F3AM.5 / 190307	WormBaseID:	WBGene00021923	Length:	365	Species:	Caenorhabditis elegans

Alignment Length:	381	Identity:	78/381 - (20%)
Similarity:	148/381 - (38%)	Gaps:	87/381 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   401 VYQIVDALRRNTNLSFDLSCEALRVVLTSLEQL---YNGAINPYLEAVAVHVTGKVATPKEL-LG 461
            |.:.||.:|..|:... ::|:   :.|.||.|:   :.|....:::      .||.:...:: :.
Worm    12 VAECVDTIRAVTDAPL-VNCD---IALQSLLQILKPHFGTCENFIQ------LGKCSESFKINVE 66

  Fly   462 ITHDAKRLQYLFAQLADCKNDTEQRTWMLYEDEEDIIQFLEELVEILINADESISCYEMSCDQYQ 526
            ..||.:.|....|.|.|...:.::.::...:|:|.|...|:...:|:...|..|....:|.:.::
Worm    67 TCHDRRVLDDAAASLFDIFQEKQELSYSAEQDDEAICTQLDAFCDIVKKTDSRIPLAVISANNWE 131

  Fly   527 MFINLVQYYQMETRWSIKRLLLKTFTAACH-----LDYIIVDILLT-SVLPLEIVEDMKTHFSNL 585
            ....|:...|.:...:::..:|........     :...::|..|: :::||       |..||.
Worm   132 WLTQLLIVLQTDQNDTVREHILSALRVLMEQCGEPVKRSLLDTQLSITLVPL-------TQKSNG 189

  Fly   586 DRFKQLVKMLTIIFSLGQ-PMPVNHQDYLGVHF----------------------ASFLLEIVEG 627
            .:...| |:|.:::|... .:|:...|||...:                      .|:|.|..:|
Worm   190 IQIPAL-KILALMYSADDVAIPLEQMDYLNTEYFRRLYRQIGDFHKIDVLELCTNFSWLTEQQQG 253

  Fly   628 NNPEVLVDMVIALILAFNQQFSEHTYNVIIEGMQNLPSAKVFTEKLLLLLNREDD--PTRLLKHP 690
            :.|           |:..|..||..|           |...|..:|:..||::..  |.:.|.|
Worm   254 SAP-----------LSIFQPISEDPY-----------SCAQFGIELIQKLNKKCSVRPLKFLSH- 295

  Fly   691 NEHMNTVLRMFIDIFSHPDTAGMFYTNDIKVLIDIVVRQLSDLDAGSTTRPCYLEL 746
                  |:.:..::.|.     |||.||:|||..::.|:..:.|.....|.|...|
Worm   296 ------VIELGEEVLSK-----MFYENDLKVLAHVLARESINHDDKQVRRLCLTSL 340

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2258	NP_001285000.1	SH3_SPIN90	1..55	CDD:212783
		PHA03420	108..>188	CDD:177648
		DUF2013	631..766	CDD:286514	28/118 (24%)
Y55F3AM.5	NP_500021.4	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4035
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13357
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000