DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment UbcE2H and ube2h

DIOPT Version :9

Sequence 1:	NP_572438.1	Gene:	UbcE2H / 31728	FlyBaseID:	FBgn0029996	Length:	183	Species:	Drosophila melanogaster
Sequence 2:	NP_958897.1	Gene:	ube2h / 368425	ZFINID:	ZDB-GENE-030616-67	Length:	183	Species:	Danio rerio

Alignment Length:	183	Identity:	142/183 - (77%)
Similarity:	162/183 - (88%)	Gaps:	0/183 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSSPSAGKRRMDNDVIKLIESKHEVTILGGLNEFHVKFFGPTETPYEGGVWKVRVYLPDNYPFKS 65
            |||||.||||||.||:||||||||||||.|||||.|||:||..||||||||||||.|||.|||||
Zfish     1 MSSPSPGKRRMDTDVVKLIESKHEVTILSGLNEFVVKFYGPQGTPYEGGVWKVRVDLPDKYPFKS 65

  Fly    66 PSIGFVNKIYHPNIDESSGTVCLDVINQAWTALYDLSNIFESFLPQLLTYPNPVDPLNRDAAALY 130
            |||||:|||:||||||:|||||||||||.|||||||:|||||||||||.||||:||||.||||:|
Zfish    66 PSIGFMNKIFHPNIDEASGTVCLDVINQTWTALYDLTNIFESFLPQLLAYPNPIDPLNGDAAAMY 130

  Fly   131 LHEPEEYHRKVADYVQRYATEDALRAAQQERESSDSESSMSDYSEDEARDMEL 183
            ||.||:|.:|:.:|:|:||||:||:..::....|.|||||||:|||||:||||
Zfish   131 LHRPEDYKQKIKEYIQKYATEEALKEQEEGPGDSSSESSMSDFSEDEAQDMEL 183

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
UbcE2H	NP_572438.1	COG5078	1..149	CDD:227410	119/147 (81%)
ube2h	NP_958897.1	COG5078	1..149	CDD:227410	119/147 (81%)
ube2h	NP_958897.1	UQ_con	31..145	CDD:278603	91/113 (81%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170576267
Domainoid	1	1.000	208	1.000	Domainoid score	I2819
eggNOG	1	0.900	-	-		E1_KOG0416
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H103894
Inparanoid	1	1.050	304	1.000	Inparanoid score	I2640
OMA	1	1.010	-	-		QHG54493
OrthoDB	1	1.010	-	-		D1301162at2759
OrthoFinder	1	1.000	-	-		FOG0003525
OrthoInspector	1	1.000	-	-		oto41662
orthoMCL	1	0.900	-	-		OOG6_102420
Panther	1	1.100	-	-	LDO	PTHR24068
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2322
SonicParanoid	1	1.000	-	-		X2404
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800