DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2256 and 1700109H08Rik

DIOPT Version :9

Sequence 1:	NP_572437.2	Gene:	CG2256 / 31727	FlyBaseID:	FBgn0029995	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_084119.1	Gene:	1700109H08Rik / 77036	MGIID:	1924286	Length:	210	Species:	Mus musculus

Alignment Length:	215	Identity:	84/215 - (39%)
Similarity:	125/215 - (58%)	Gaps:	25/215 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 KLLDSLRKKTR-FTKDELDALCRIYRKLVSNCQYAAKTLASSSSSAAIAKPHAAVE--GIDRIVF 172
            |:::|:||..: |.|.|::.|.|::..|| .|                  |...::  |:|...|
Mouse     8 KMVESIRKTVKSFKKFEVECLIRLFYSLV-GC------------------PVGKMDNTGLDCNTF 53

  Fly   173 RELLHSTFDIVTEEILMERIFCSWDKAHEGLPLRLEGWLIGLSTFLRGTPAERAAFCFRVYDLNT 237
            |.:|.:.|. :|.::||.|:|..:||..:|. :.||.|:.||:.|||||..|:..|||.||.||.
Mouse    54 RGVLQNIFG-MTNDMLMNRVFFVFDKDGDGY-VNLEEWIKGLAVFLRGTFEEKMRFCFEVYYLNG 116

  Fly   238 DGFITKDEMFTLLRNCLIKQPQDEDPDEGVKDLVEIVLKKFDLDKDGKVSLEDFMGTVTAEPLLI 302
            |.:|:::::|.:|::.|.:...:|:.:|||||||||.|||.|.|.|||:|..||...|..:.||:
Mouse   117 DAYISQEKIFDMLKSSLFQHSPEEENEEGVKDLVEISLKKMDYDNDGKISFADFEKAVKEDGLLL 181

  Fly   303 EAFGQCLPTDSAVVSFFSTL 322
            ||||.||| |:.....|..|
Mouse   182 EAFGPCLP-DAKFCFHFEAL 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	EFh	228..292	CDD:238008	32/63 (51%)
CG2256	NP_572437.2	EF-hand_7	229..292	CDD:290234	31/62 (50%)
1700109H08Rik	NP_084119.1	EFh	71..130	CDD:298682	26/59 (44%)
1700109H08Rik	NP_084119.1	EF-hand_7	105..174	CDD:290234	33/68 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167833418
Domainoid	1	1.000	96	1.000	Domainoid score	I7312
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	173	1.000	Inparanoid score	I4073
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005764
OrthoInspector	1	1.000	-	-		otm43720
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	12	11.850