Protein Alignment CG2256 and Ncs1

DIOPT Version :10

• Sequence 1: NP_572437.2
• Gene: CG2256 / 31727
• FlyBaseID: FBgn0029995
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_077342.1
• Gene: Ncs1 / 65153
• RGDID: 68417
• Length: 190
• Species: Rattus norvegicus
• Alignment Length: 213
• Identity: 49/213 - (23%)
• Similarity: 101/213 - (47%)
• Gaps: 40/213 - (18%)

  Fly   101 MDELSGKVNPKLLDSLRKKTRFTKDELDALCRIYRKLVSNCQYAAKTLASSSSSAAIAKPHAAVE 165
            |.:.:.|:.|::::.|.:||.||:.|:.   :.|:..:.:|....
  Rat     1 MGKSNSKLKPEVVEELTRKTYFTEKEVQ---QWYKGFIKDCPSGQ-------------------- 42

  Fly   166 GIDRIVFRELLHSTFDIVTEEILMERIFCSWDKAHEGLPLRLE--GWLIGLSTFLRGTPAERAAF 228
             :|...|:::....|...........:|..:|:..:|   |:|  .::..||...|||..|:..:
  Rat    43 -LDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDG---RIEFSEFIQALSVTSRGTLDEKLRW 103

  Fly   229 CFRVYDLNTDGFITKDEM-------FTLLRNCLIKQPQDEDPDEGVKDLVEIVLKKFDLDKDGKV 286
            .|::|||:.||:||::||       :.::.| .::.|::|:..|   ..|:.:....|.:.|||:
  Rat   104 AFKLYDLDNDGYITRNEMLDIVDAIYQMVGN-TVELPEEENTPE---KRVDRIFAMMDKNADGKL 164

  Fly   287 SLEDFMGTVTAEPLLIEA 304
            :|::|.....|:|.:::|
  Rat   165 TLQEFQEGSKADPSIVQA 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	PRK12309	<103..290	CDD:183426	44/195 (23%)
		EF-hand_7	224..292	CDD:463900	21/74 (28%)
Ncs1	NP_077342.1	FRQ1	22..174	CDD:444056	40/182 (22%)
		Ancestral calcium site 1	36..47		2/31 (6%)
		Interaction with IL1RAPL1. /evidence=ECO:0000250|UniProtKB:P62166	174..190		3/9 (33%)