DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2256 and Kcnip2

DIOPT Version :9

Sequence 1:	NP_572437.2	Gene:	CG2256 / 31727	FlyBaseID:	FBgn0029995	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_064479.2	Gene:	Kcnip2 / 56817	RGDID:	70887	Length:	270	Species:	Rattus norvegicus

Alignment Length:	226	Identity:	65/226 - (28%)
Similarity:	108/226 - (47%)	Gaps:	40/226 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    79 SNQQSKAAAAALQNKRQQRQRRMD--------ELSGKVN-PKLLDSLRKKTRFTKDELDALCRIY 134
            |..::.||.|:|   |..|.|.:|        |||...: |:.|:.|:::|:||:.||..|   |
  Rat    53 SVSETLAAPASL---RPHRPRPLDPDSVEDEFELSTVCHRPEGLEQLQEQTKFTRRELQVL---Y 111

  Fly   135 RKLVSNCQYAAKTLASSSSSAAIAKPHAAVEGIDRIVFRELLHSTFDIVTEEILMERIFCSWDKA 199
            |...:.|                  |...|...:   |:::....|...........:|.::|..
  Rat   112 RGFKNEC------------------PSGIVNEEN---FKQIYSQFFPQGDSSNYATFLFNAFDTN 155

  Fly   200 HEGLPLRLEGWLIGLSTFLRGTPAERAAFCFRVYDLNTDGFITKDEMFTLLRNCLIKQPQDEDP- 263
            |:| .:..|.::.|||..||||..:|.::.|.:||||.||.|||:||..::::......:...|
  Rat   156 HDG-SVSFEDFVAGLSVILRGTIDDRLSWAFNLYDLNKDGCITKEEMLDIMKSIYDMMGKYTYPA 219

  Fly   264 --DEGVKDLVEIVLKKFDLDKDGKVSLEDFM 292
              :|..::.||...:|.|.:|||.|::|:|:
  Rat   220 LREEAPREHVESFFQKMDRNKDGVVTIEEFI 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	EFh	228..292	CDD:238008	23/66 (35%)
CG2256	NP_572437.2	EF-hand_7	229..292	CDD:290234	23/65 (35%)
Kcnip2	NP_064479.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..34
		FRQ1	93..259	CDD:227455	52/183 (28%)
		Interaction with KCND2. /evidence=ECO:0000250\|UniProtKB:Q8R426	257..270
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810