DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2256 and efcab1

DIOPT Version :9

Sequence 1:	NP_572437.2	Gene:	CG2256 / 31727	FlyBaseID:	FBgn0029995	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_001016778.1	Gene:	efcab1 / 549532	XenbaseID:	XB-GENE-5727529	Length:	208	Species:	Xenopus tropicalis

Alignment Length:	225	Identity:	96/225 - (42%)
Similarity:	135/225 - (60%)	Gaps:	30/225 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 RQQRQRRMDELSGKVNPKLLDSLRKKTRFTKDELDALCRIYRKLVSNCQYAAKTLASSSSSAAIA 158
            |:..|::.|.||           |....|:|:|:::|.|:|..||..                ..
Frog     3 RKNLQKQADALS-----------RLIKHFSKNEVESLIRLYHTLVGR----------------PI 40

  Fly   159 KPHAAVEGIDRIVFRELLHSTFDIVTEEILMERIFCSWDKAHEGLPLRLEGWLIGLSTFLRGTPA 223
            .|:.. .||||..||.:||:||. :|::::|:|:|..:||.::.. :.:..|:.|||.|||||..
Frog    41 DPNTR-RGIDRNTFRNILHNTFG-MTDDMIMDRVFRGFDKDNDSY-ISVTEWVEGLSVFLRGTLE 102

  Fly   224 ERAAFCFRVYDLNTDGFITKDEMFTLLRNCLIKQPQDEDPDEGVKDLVEIVLKKFDLDKDGKVSL 288
            ||..:||.|||||.||:|:::|||.:|:|.|:|||.:|||||||||||||.|||.|.|.|.|:|.
Frog   103 ERIKYCFGVYDLNGDGYISREEMFHMLKNSLLKQPSEEDPDEGVKDLVEIALKKMDYDHDSKLSY 167

  Fly   289 EDFMGTVTAEPLLIEAFGQCLPTDSAVVSF 318
            .||...|..|.||:||||.|||....:::|
Frog   168 MDFEKAVQEENLLLEAFGPCLPDSKCIMAF 197

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	EFh	228..292	CDD:238008	41/63 (65%)
CG2256	NP_572437.2	EF-hand_7	229..292	CDD:290234	41/62 (66%)
efcab1	NP_001016778.1	EF-hand_7	69..129	CDD:290234	29/60 (48%)
		EFh	71..130	CDD:238008	28/59 (47%)
		EFh	104..175	CDD:238008	43/70 (61%)
		EF-hand_7	105..174	CDD:290234	42/68 (62%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7234
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H11608
Inparanoid	1	1.050	171	1.000	Inparanoid score	I3995
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1331864at2759
OrthoFinder	1	1.000	-	-		FOG0005764
OrthoInspector	1	1.000	-	-		oto104394
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5830
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	11.100