DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2256 and LOC500007

DIOPT Version :9

Sequence 1:	NP_572437.2	Gene:	CG2256 / 31727	FlyBaseID:	FBgn0029995	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	XP_006236139.1	Gene:	LOC500007 / 500007	RGDID:	1588445	Length:	217	Species:	Rattus norvegicus

Alignment Length:	218	Identity:	81/218 - (37%)
Similarity:	123/218 - (56%)	Gaps:	31/218 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly   111 KLLDSLRKKTR-FTKDELDALCRIYRKLVSNCQYAAKTLASSSSSAAIAKPHAAVEG--IDRIVF 172
            ||::|.||..: |.|.|::.|.:::..| :.|                  |...|:.  :|...|
  Rat     8 KLVESFRKTVKCFKKFEVECLIQLFYSL-AGC------------------PIGKVDNTKLDCNAF 53

  Fly   173 RELLHSTFDIVTEEILMERIFCSWDK---AHEGLPLRLEGWLIGLSTFLRGTPAERAAFCFRVYD 234
            |.:|.:.|. :|.::||.|:|..:||   :|    :.|:.|:.||:.|||||..|:..|||.||.
  Rat    54 RGVLQNFFG-MTNDVLMNRVFFVFDKDGDSH----VNLQEWIKGLAVFLRGTFEEKMRFCFEVYY 113

  Fly   235 LNTDGFITKDEMFTLLRNCLIKQPQDEDPDEGVKDLVEIVLKKFDLDKDGKVSLEDFMGTVTAEP 299
            |:.|.:|:::::|.:|::.|.....:|:.:||:||||||.|||.|.|.|||:|.|||...|..:.
  Rat   114 LSGDAYISREKIFDMLKSSLFHNSPEEENEEGIKDLVEISLKKMDYDNDGKISFEDFEKAVRKDG 178

  Fly   300 LLIEAFGQCLPTDSAVVSFFSTL 322
            ||:||||.||| |:.....|..|
  Rat   179 LLLEAFGPCLP-DAKTCFHFEAL 200

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	EFh	228..292	CDD:238008	31/63 (49%)
CG2256	NP_572437.2	EF-hand_7	229..292	CDD:290234	30/62 (48%)
LOC500007	XP_006236139.1	EFh	104..175	CDD:298682	32/70 (46%)
LOC500007	XP_006236139.1	EF-hand_7	105..174	CDD:290234	32/68 (47%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166336973
Domainoid	1	1.000	96	1.000	Domainoid score	I7142
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	171	1.000	Inparanoid score	I4020
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1331864at2759
OrthoFinder	1	1.000	-	-		FOG0005764
OrthoInspector	1	1.000	-	-		otm45796
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR23055
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.860