Protein Alignment CG2256 and HPCA

DIOPT Version :10

• Sequence 1: NP_572437.2
• Gene: CG2256 / 31727
• FlyBaseID: FBgn0029995
• Length: 324
• Species: Drosophila melanogaster
• Sequence 2: NP_002134.2
• Gene: HPCA / 3208
• HGNCID: 5144
• Length: 193
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 50/220 - (22%)
• Similarity: 105/220 - (47%)
• Gaps: 35/220 - (15%)

  Fly   101 MDELSGKVNPKLLDSLRKKTRFTKDELDALCRIYRKLVSNCQYAAKTLASSSSSAAIAKPHAAVE 165
            |.:.:.|:.|::|..||:.|.|::.||.   ..|:..:.:|.                   ..:.
Human     1 MGKQNSKLRPEMLQDLRENTEFSELELQ---EWYKGFLKDCP-------------------TGIL 43

  Fly   166 GIDRIVFRELLHSTFDIVTEEILMERIFCSWDKAHEGLPLRLEGWLIGLSTFLRGTPAERAAFCF 230
            .:|.  |:::..:.|.........|.:|.::|...:| .:....::|.||...||...::..:.|
Human    44 NVDE--FKKIYANFFPYGDASKFAEHVFRTFDTNSDG-TIDFREFIIALSVTSRGRLEQKLMWAF 105

  Fly   231 RVYDLNTDGFITKDEMFTLLR------NCLIKQPQDEDPDEGVKDLVEIVLKKFDLDKDGKVSLE 289
            .:|||:.:|:|:::||..:::      :.::|.|:||...|   ...|.:.::.|.:.|||:|||
Human   106 SMYDLDGNGYISREEMLEIVQAIYKMVSSVMKMPEDESTPE---KRTEKIFRQMDTNNDGKLSLE 167

  Fly   290 DFMGTVTAEPLLIEAFGQCLPTDSA 314
            :|:....::|.::... ||.|:.::
Human   168 EFIRGAKSDPSIVRLL-QCDPSSAS 191

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	PRK12309	<103..290	CDD:183426	43/192 (22%)
		EF-hand_7	224..292	CDD:463900	21/73 (29%)
HPCA	NP_002134.2	FRQ1	41..175	CDD:444056	34/139 (24%)