DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG2256 and KCNIP3

DIOPT Version :10

Sequence 1:NP_572437.2 Gene:CG2256 / 31727 FlyBaseID:FBgn0029995 Length:324 Species:Drosophila melanogaster
Sequence 2:NP_038462.1 Gene:KCNIP3 / 30818 HGNCID:15523 Length:256 Species:Homo sapiens


Alignment Length:190 Identity:53/190 - (27%)
Similarity:92/190 - (48%) Gaps:36/190 - (18%)


- Green bases have known domain annotations that are detailed below.


  Fly   110 PKLLDSLRKKTRFTKDELDALCRIYRKLVSNCQYAAKTLASSSSSAAIAKPHAAVEGIDRIVFRE 174
            |:.||.|:.:|:|||.||.:|   ||...:.|....                     :|...|: 
Human    76 PEGLDQLQAQTKFTKKELQSL---YRGFKNECPTGL---------------------VDEDTFK- 115

  Fly   175 LLHSTF----DIVTEEILMERIFCSWDKAHEGLPLRLEGWLIGLSTFLRGTPAERAAFCFRVYDL 235
            |:::.|    |..|   ....:|.::|....| .:..|.:::|||..||||..|:..:.|.:||:
Human   116 LIYAQFFPQGDATT---YAHFLFNAFDADGNG-AIHFEDFVVGLSILLRGTVHEKLKWAFNLYDI 176

  Fly   236 NTDGFITKDEMFTLLRNCLIKQPQDEDP---DEGVKDLVEIVLKKFDLDKDGKVSLEDFM 292
            |.||:|||:||..::::......:...|   ::...:.||...:|.|.::||.|::|:|:
Human   177 NKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDRNQDGVVTIEEFL 236

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG2256NP_572437.2 PRK12309 <103..290 CDD:183426 51/186 (27%)
EF-hand_7 224..292 CDD:463900 21/70 (30%)
KCNIP3NP_038462.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..20
FRQ1 107..241 CDD:444056 39/156 (25%)
Interaction with KCND2. /evidence=ECO:0000250 243..256
Blue background indicates that the domain is not in the aligned region.

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