DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2256 and Kcnip4

DIOPT Version :9

Sequence 1:	NP_572437.2	Gene:	CG2256 / 31727	FlyBaseID:	FBgn0029995	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_852030.1	Gene:	Kcnip4 / 259243	RGDID:	708539	Length:	250	Species:	Rattus norvegicus

Alignment Length:	220	Identity:	59/220 - (26%)
Similarity:	101/220 - (45%)	Gaps:	45/220 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    83 SKAAAAALQNKRQQRQRRMDEL---SGKVNPKLLDSLRKKTRFTKDELDALCRIYRKLVSNCQYA 144
            :|.::.|:||..:      |||   :.:..|:.|:.|..:::|||.||..|   ||...:.|
  Rat    46 AKTSSPAIQNSVE------DELEMATVRHRPEALELLEAQSKFTKKELQIL---YRGFKNEC--- 98

  Fly   145 AKTLASSSSSAAIAKPHAAVEGIDRIVFRELLHSTFDIVTEEILMERIFCSWDKAHEGLPLRLEG 209
                           |...|   :...|:|:....|...........:|.::|..|.| .:..|.
  Rat    99 ---------------PSGVV---NEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNG-AVSFED 144

  Fly   210 WLIGLSTFLRGTPAERAAFCFRVYDLNTDGFITKDEMFTLLR-------NCLIKQPQDEDPDEGV 267
            ::.|||..||||..|:..:.|.:||:|.||:|||:||..:::       .|.....:::.|
  Rat   145 FIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMMGKCTYPVLKEDAP---- 205

  Fly   268 KDLVEIVLKKFDLDKDGKVSLEDFM 292
            :..||...:|.|.:|||.|::::|:
  Rat   206 RQHVETFFQKMDKNKDGVVTIDEFI 230

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2256	NP_572437.2	EFh	228..292	CDD:238008	21/70 (30%)
CG2256	NP_572437.2	EF-hand_7	229..292	CDD:290234	21/69 (30%)
Kcnip4	NP_852030.1	KIS. /evidence=ECO:0000250	2..44
		FRQ1	80..239	CDD:227455	49/180 (27%)
		Interaction with KCND2. /evidence=ECO:0000250	237..250
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0044
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X31
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810